RE: I'm just curious RE: PSC and clotting disorders/

[Guest guest]

With cirrhosis (liver tissue replaced by fibrotic scar tissue), the prothrombin time (measure of how fast your blood clots) increases. The liver synthesizes clotting factors, and is much less effective at doing this as scarring progresses. As a result, you may have difficulty clotting. This would be the opposite of what your Drs. appear to be trying (aspirin decreases clotting).

I don't believe you've ever stated whether you have UC or Crohn's, which also may affect clotting (excessive generation of thrombin). See http://www.emedicine.com/emerg/topic150.htm, for instance, which is treated with anticoagulants. Note the section on pregnancy/obstetrics.

For those medically trained - please correct me if I'm wrong.

Arne

56 - UC 1977, PSC 2000

Alive and (mostly) well in Minnesota

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From: [mailto: ] On Behalf Of jmhette2

....So I guess my question is....how does liver disease cause clotting disorders?...