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Hi everyone! I am 24 and live in Charlotte, NC. I was diagnosed with

PSC about 6 months ago. I have never had any symptoms but did have

very high liver enzymes once when I had my blood work done on a

routine check-up. I went through what felt like a million tests

until two doctors confirmed PSC.

I started taking Urso immediately but my hair started changing

texture and falling out and I really didn't feel like myself. I told

my doctors who then left it up to me to decide whether to continue on

taking it. I stopped taking it about 3 months ago and feel great

now. My hair is back to normal and still no symptoms. My tests for UC

were negative too.

I personally feel like my doctors (whom I really like and trust) came

to this conclusion based on valid evidence of the tests taken,

however, I kind of have my own hypothesis. I had an eating disorder

in college and was very underweight for about 3 years. Upon recovery

I have gained about 35 pounds in only about a year. Yikes I know...I

think my liver has been damaged as a result. The doctors have

touched on the subject briefly, but don't want to really use that as

an explanation for my test results. I'm just confused I guess and am

not sure what to do now that I'm not taking the urso. I am taking

Milk Thistle and watching my diet. I have also really gotten into

Hot Yoga. I sweat like crazy and hope this may help release some

built up toxins. I have stopped drinking completely. This is really

important right..to stop drinking? Alright, I think I've commented

enough and sorry for the long explanations. Any advice would be

wonderful and thank you in advance.

Sally

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Welcome to the group! It is interesting to me that you said you suffered from

an eating disorder. I did too (anorexia) and I thought that it was my fault

that I ended up sick. My doc said no. Now whether that is true or he just

wanted me to feel better, I don't know.

I do take Urso and I have had no side effects. I know that the Urso thins the

bile to allow it to move more easily but I don't know that there is any evidence

that it does anything to slow the progression of the disease. I also do not

have any problems related to my liver and it has been six years for me. I do

not drink at all and I don't think that they recommend any level of alcohol use.

Do you have UC or Crohn's?

PSC '01

Crohns

>>> " salwright83 " 10/8/2007 7:35 AM >>>

Hi everyone! I am 24 and live in Charlotte, NC. I was diagnosed with

PSC about 6 months ago. I have never had any symptoms but did have

very high liver enzymes once when I had my blood work done on a

routine check-up. I went through what felt like a million tests

until two doctors confirmed PSC.

I started taking Urso immediately but my hair started changing

texture and falling out and I really didn't feel like myself. I told

my doctors who then left it up to me to decide whether to continue on

taking it. I stopped taking it about 3 months ago and feel great

now. My hair is back to normal and still no symptoms. My tests for UC

were negative too.

I personally feel like my doctors (whom I really like and trust) came

to this conclusion based on valid evidence of the tests taken,

however, I kind of have my own hypothesis. I had an eating disorder

in college and was very underweight for about 3 years. Upon recovery

I have gained about 35 pounds in only about a year. Yikes I know...I

think my liver has been damaged as a result. The doctors have

touched on the subject briefly, but don't want to really use that as

an explanation for my test results. I'm just confused I guess and am

not sure what to do now that I'm not taking the urso. I am taking

Milk Thistle and watching my diet. I have also really gotten into

Hot Yoga. I sweat like crazy and hope this may help release some

built up toxins. I have stopped drinking completely. This is really

important right..to stop drinking? Alright, I think I've commented

enough and sorry for the long explanations. Any advice would be

wonderful and thank you in advance.

Sally

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>>>I

thought that it was my fault that I ended up sick. My

doc said no. Now whether that is true or he just

wanted me to feel better, I don't know.

Ladies,

I don’t have a

dog in this hunt, but I can tell you both – neither of you caused your

PSC! It happened, it’s no one’s

fault.

With love, Barb in Texas - Together in the Fight, Whatever it Takes!

Son Ken (33) UC 91 - PSC 99 - Tx 6/21 & 6/30/07 @ Baylor in Dallas

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Thanks Barb! I will say that the PSC, and all the joy that goes with it, made

me realize that I had to get my life to a better place.............and I did. I

guess that is actually a blessing that PSC brought.

- Also in Texas :)

>>> " Barb Henshaw " 10/8/2007 10:25 AM >>>

>>>I thought that it was my fault that I ended up sick. My doc said no.

Now whether that is true or he just wanted me to feel better, I don't

know.

Ladies,

I don't have a dog in this hunt, but I can tell you both - neither of

you caused your PSC! It happened, it's no one's fault.

With love, Barb in Texas - Together in the Fight, Whatever it Takes!

Son Ken (33) UC 91 - PSC 99 - Tx 6/21 & 6/30/07 @ Baylor in Dallas

===========================================================

This message is confidential, intended only

for the named recipient(s) and may contain

information that is privileged or exempt from

disclosure under applicable law. If you are

not the intended recipient(s), you are notified

that the dissemination, distribution or copying

of this message is strictly prohibited. If you

received this message in error, or are not the

named recipient(s), please notify the sender

and delete this e-mail from your computer.

ETMC has implemented secure messaging for

certain types of messages. For more information

about our secure messaging system, go to:

http://www.etmc.org/mail/

Thank you.

===========================================================

BEGIN:VCARD

VERSION:2.1

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EMAIL;WORK;PREF;NGW:lindawilkinson@...

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Dear Sally,

Sorry to hear you may have PSC but glad you found our support group. I wanted to

reach out to you because I also live in Charlotte and have PSC and UC. There are

a couple of us in the area and a few more in NC.

I was disappointed to hear you had trouble tolerating the Urso. You are not

alone. I know Caroline in SC has not been able to take it and there are others.

I am currently on the High Dose Urso Study being conducted by the Mayo Clinic

and I will have my 5 year tests done this December to evaluate my reaction to

the drug or placebo. Obviously, these tests are being done to determine if Urso

can slow the disease down. So we still don't know if Urso is the answer or not.

I know you said you were taking Milk Thistle. Another recommendation would be to

take an Omega-3 fish oil supplement. There are ongoing studies into the benefits

of DHA (Docosahexaenoic Acid) on PSC and many of us take it. There are added

cardiovascular benefits with this supplement as well.

Please feel free to contact me if you want to chat. We are in the phone book.

Tarheel-Tim Wholey

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Hi Tim,

I read that you said that you are involoved in a Study with Mayo and Urso. My husband takes URSO as well and we were wondering if there were any studies at Mayo since we live in Phoenix AZ. Mayo is in the next town sdale. Any leads on how to get him inot study?? Does anyone live in AZ who has PSC? Thanks Pamela

-- Re: Also new to PSC...

Dear Sally,Sorry to hear you may have PSC but glad you found our support group. I wanted to reach out to you because I also live in Charlotte and have PSC and UC. There are a couple of us in the area and a few more in NC.I was disappointed to hear you had trouble tolerating the Urso. You are not alone. I know Caroline in SC has not been able to take it and there are others. I am currently on the High Dose Urso Study being conducted by the Mayo Clinic and I will have my 5 year tests done this December to evaluate my reaction to the drug or placebo. Obviously, these tests are being done to determine if Urso can slow the disease down. So we still don't know if Urso is the answer or not.I know you said you were taking Milk Thistle. Another recommendation would be to take an Omega-3 fish oil supplement. There are ongoing studies into the benefits of DHA (Docosahexaenoic Acid) on PSC and many of us take it. There are added cardiovascular benefits with this supplement as well.Please feel free to contact me if you want to chat. We are in the phone book.Tarheel-Tim Wholey

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Pamela,

I don't know if they are accepting any new study participants or not. If they

are, a call to the sdale Mayo clinics Hepatology/Gastro group would get you

started. Otherwise call Mayo Rochester at and ask for Jill.

All the best,

Tarheel Tim

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