UC and Pancreatitis

[Guest guest]

One of my pancreatitis questions I just posed may have been answered.

The cause of the " P " may be the UC, not the PSC (but the ROOT is the

PSC, cause if Fred didn't have the PSC, he probably wouldn't have the

UC - you see?

Dave had posted this article recently - and I believe Fred may

be one of the 1/6 of UC patients that has pancreatic duct abnormalities.

Pancreas duct abnormalities in patients with ulcerative colitis: a

magnetic resonance pancreatography study.

Toda N, Akahane M, Kiryu S, Matsubara Y, Yamaji Y, Okamoto M,

Minagawa N, Ohgi K, Komatsu Y, Yahagi N, Yoshida H, Kawabe T, Ohtomo

K, Omata M

Division of Gastroenterology, Department of Internal Medicine,

University of Tokyo, Japan. ntoda@...

BACKGROUND: The presumed etiology and prevalence of pancreatic

abnormalities in patients with ulcerative colitis (UC) have been

controversial. We conducted a controlled (cross-sectional) study of

patients with UC compared with non-UC controls to determine the

prevalence of pancreatic duct abnormalities in patients with UC and

to determine if these are specific to UC using magnetic resonance

cholangiopancreatography. METHODS: Magnetic resonance

cholangiopancreatography was performed on 79 unselected patients with

UC and 45 non-UC controls, without a history of pancreatitis attack,

between February 2000 and May 2003. RESULTS: Among patients with UC,

the prevalence of pancreatic duct abnormalities was 16.4% (95%

confidence interval, 8.3%-24.6%): coexisting dilatation and narrowing

of the main pancreatic duct were found in 5; diffuse narrowing of

pancreatic ducts in 5; and dilatation of pancreatic ductal branches

in 3. These abnormalities were compatible with chronic pancreatitis.

Among the controls, no pancreatic duct abnormality was found.

CONCLUSIONS: Changes in the pancreatic duct were found in

approximately one-sixth of patients with UC, none of whom had a

history of overt pancreatitis. These pancreatic duct abnormalities

are likely to be specific to patients with UC. PMID: 16189420.

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Wife of Fred, PSC/UC/, etc.

[Guest guest]

Very interesting article. My docs have been telling me for nearly 24 years that the pancreatic ducts may/are affected because of the PSC. Hmmm!

PSC, UC dx 1984, chronic pancreatitis dx 1997, etc.; listed for tx 06/05 in STL, and 06/07 in Clevelandhttp://www.caringbridge.org/visit/melaniejsSee what's new at AOL.com and Make AOL Your Homepage.