LIDOCAINE Cottonball treatment OVERNIGHT FOR V V

[Guest guest]

For the newbies, vv stands for vulvar vestibulitis or vvs, the 's' meaning syndrome. Most of us have the 5% Lidocaine compounded in a soothing base. I've tried it straight from a manufacturer (Rx needed)...but I can only tolerate the 5% if it's compounded. Chelle

In case some of you arent aware of this study. Dee~

ORIGINAL RESEARCH

Overnight 5% Lidocaine Ointment for Treatment of Vulvar Vestibulitis Denniz A. Zolnoun, MD, MPH , E. Hartmann, MD, PhD and F. Steege, MD From the Department of Obstetrics and Gynecology, University of North Carolina School of Medicine, Chapel Hill, North Carolina.

Address reprint requests to: Denniz Zolnoun, MD, MPH, CB#7570, University of North Carolina, School of Medicine, Chapel Hill, NC 27599-7570; E-mail: denniz_zolnoun (AT) med (DOT) unc.edu

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OBJECTIVE: To assess the effectiveness of nightly application of 5% lidocaine ointment for treatment of vulvar vestibulitis.

METHODS: Over 17 months, we assessed women presenting to our pain clinic for evaluation of introital pain; 61 women met the criteria for vulvar vestibulitis and participated in a treatment trial. We measured daily pain and intercourse-related pain using a 100-mm visual analog scale. We compared ability to have intercourse and pain ratings before and after treatment, and investigated whether prior treatment or gynecologic comorbidities predicted response to treatment.

RESULTS: After a mean of 7 weeks of nightly treatment, 76% of women reported ability to have intercourse, compared with 36% before treatment (P = .002). Intercourse-related pain score was 39.11 (95% confidence interval [CI] 30.39, 47.83) points lower after treatment (P < .001), with a decrease of 10.37 (95% CI 3.53, 17.21) points in daily pain score (P = .004).

We found no association between response to prior episodic use of lidocaine and response to nightly therapy with lidocaine ointment. Few patient characteristics predicted response to treatment; however, women with interstitial cystitis and other vulvar conditions were least likely to benefit.

CONCLUSION: Long-term, nightly application of 5% lidocaine ointment shows promise as a treatment for management of vulvar vestibulitis; a randomized, double-blind, clinical trial is warranted.

[Guest guest]

And how is that different from lichen schlerosis or Atrophic Vulvar Dystrophy?I have been over whelmed with all of the wonderful emails but don't know if I am in the right place because most emails don't mention my diagnoses.Thank you!JoanFor the newbies, vv stands for vulvar vestibulitis or vvs, the 's' meaning syndrome.  Most of us have the 5% Lidocaine compounded in a soothing base.  I've tried it straight from a manufacturer (Rx needed)...but I can only tolerate the 5% if it's compounded.  Chelle--- On Tue, 1/23/07, DeeTroll <dtroll (AT) cboss (DOT) com> wrote:In case some of you arent aware of this study.  Dee~ ORIGINAL RESEARCHOvernight 5% Lidocaine Ointment for Treatment of Vulvar VestibulitisDenniz A. Zolnoun, MD, MPH , E. Hartmann, MD, PhD and F. Steege, MDFrom the Department of Obstetrics and Gynecology, University of North Carolina School of Medicine, Chapel Hill, North Carolina.Address reprint requests to: Denniz Zolnoun, MD, MPH, CB#7570, University of North Carolina, School of Medicine, Chapel Hill, NC 27599-7570; E-mail:denniz_zolnoun (AT) med (DOT) unc.edu .OBJECTIVE: To assess the effectiveness of nightly application of 5% lidocaine ointment for treatment of vulvar vestibulitis.METHODS: Over 17 months, we assessed women presenting to our pain clinic for evaluation of introital pain; 61 women met the criteria for vulvar vestibulitis and participated in a treatment trial.We measured daily pain and intercourse-related pain using a 100-mm visual analog scale. We compared ability to have intercourse and pain ratings before and after treatment, and investigated whether prior treatment or gynecologic comorbidities predicted response to treatment.RESULTS: After a mean of 7 weeks of nightly treatment, 76% of women reported ability to have intercourse, compared with 36% before treatment (P = .002).Intercourse-related pain score was 39.11 (95% confidence interval [CI] 30.39, 47.83) points lower after treatment (P < .001), with a decrease of 10.37 (95% CI 3.53, 17.21) points in daily pain score (P = .004).We found no association between response to prior episodic use of lidocaine and response to nightly therapy with lidocaine ointment.Few patient characteristics predicted response to treatment; however, women with interstitial cystitis and other vulvar conditions were least likely to benefit.CONCLUSION: Long-term, nightly application of 5% lidocaine ointment shows promise as a treatment for management of vulvar vestibulitis; a randomized, double-blind, clinical trial is warranted.