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This was posted by a friend who knew that I was taking SAM-e. I'm including

the whole bulletin because there are other items of interest.

Penny

You are receiving this email from American Liver

Foundation because you have expressed

interest and

support for our work. To ensure that you

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------------------------------------------------------------

2007

The Monday Update

American Liver Foundation Newsletter

Greetings!

This newsletter aims to keep you up to date

with the

latest developments in the areas of liver

medicine

and science.

Here are the top liver news stories for the past

week.

~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

FDA Approves Nexavar For Liver Cancer Therapy

The US Food and Drug Administration (FDA) has

approved Nexavar (sorafenib) tablets, a supplemental

NDA (new drug application) for patients with liver

cancer. It is the first approved systemic drug therapy

for liver cancer, as well as being the only medication

therapy proven to significantly improve overall survival

in liver cancer patients.

L. Boyer, M.D., Chairman, American Liver

Foundation, said " The American Liver Foundation

(ALF) is always pleased when new therapies prove

effective for those affected by liver disease.

Researchers worldwide, including those supported by

ALF, have spent decades studying liver cancer. This

new treatment provides a valuable option for liver

cancer patients and will enable ALF to further promote

the treatment of liver disease through our education

and advocacy efforts. "

* Medical News Today -

http://rs6.net/tn.jsp?e=001KwTkTmzNaaT3agE2uAWprV6plQSBra48apRN1oLAXrRJ1WaUogQz3\

FfytfZKPFzJ7jcQlMDKPqlRsXLQaw2BGC0h2khAE9Gwg149PN4YO13E1e1xcLxnW7nkpAyV0CrmtXxPl\

JmThxT3ApBx35eI3g==

~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

New Organ Allocation Criteria Associated With Decreased Deaths On

Liver Transplant Waiting List

Changing the method by which donated livers are

allocated to potential transplant patients appears to

have decreased the number of deaths among

individuals on the waiting list as well as shortened the

time to transplantation, according to a report in the

Archives of Surgery.

* Science Daily -

http://rs6.net/tn.jsp?e=001KwTkTmzNaaQOc5gqm3ulhlJIbMX-DSZuxFnot0rXf1bkg_HCOG9xO\

T3_tu3Lhld7YA41fVqN-Zrj9iSO13JXkXbVO9kwBMdTj4DNCarIaFZJHS8AD8VVnYLsOOtqfcurv2ESv\

9WRWCVKxY-2MfxA6ltCscrPeFhgfffUK_FnedE=

~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

Arthritis drug withdrawn over liver damage fears

The license for Prexige, an arthritis drug that has been

avaiable in the UK since 2005, has been suspended

amid concerns that it may cause liver damage.

Brittish regulators ordered Prexige to be withdrawn

from the market immediately.

The drug was used to treat painful symptoms of

osteoarthritis of the knee and hip

The drug was used to treat painful symptoms of

osteoarthritis of the knee and hip.

There have been 23 reports of suspected adverse

reactions to lumiracoxib in the UK since March 2006,

three of which related to liver problems, although none

of the reactions were said to have been severe.

* Daily Mail -

http://rs6.net/tn.jsp?e=001KwTkTmzNaaQ9972AzPa5MFiu9EHl0Qk5E-iOPwJOF5_jw08Lp6K0s\

5KmpaOj-PVa_-xJl8b7bysEH96QLt3fpAaUOpmtCMnHgBfVSqrKZcR8QicyAOioe0cHeHhuitta2IAAU\

4wqMRAJoY8yDG27-wX12bGTT0J-bjd6-cXYzTeQbypcTReGxLFTTCzlM6xfoAxMIjlelpv2dFCKZoWiW\

SUBeJYhCbhWlOZdRg-CI5fv6DlTc__5YknfCYuoLffxzOLXvbhY2Ck=

~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

SAMe and Liver Disease

Study Shows Supplement May be Help Alcoholics

The supplement SAMe which proved disappointing as

a treatment for arthritis and depression as it was

originally promoted, may now offer some hope for

those who suffer from chronic liver disease.

A study by the Univerisity of California in 1999

researched how SAMe worked for alcoholics. The

study published in the Journal of Hepatology showed

that a group of alcoholics who received SAMe had a 30

percent reduction in deaths and liver transplants,

compared with a group of patients who did not receive

the supplement.

..

Research has shown that patients with alcoholic liver

disease and other liver disorders have abnormal

methionine metabolism, which depletes SAMe. Taking

therapeutic doses of SAMe helps reverse that affect

* About.com: Alcohol -

http://rs6.net/tn.jsp?e=001KwTkTmzNaaS15z1EjWwGtkb6r3nUcD3iTCyzO3hH0rY-W9GhvwTHj\

Y2FQzh786AkZFrPAcfJqYAf73esaIkN7alFDJJYpIaf2_1puZOmSZyiZ-Qy_N6cbxjxUZOqIjxFKMlxn\

puTstdY7CiQrs-6RvxiOX-mWQt8

~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

email: lneier@...

phone:

web: http://www.liverfoundation.org

~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

Thank you for your continued support of the

American Liver Foundation. For more

information on

liver disease or our work as an organization,

please

visit our website or contact your local ALF

chapter.

Forward email

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