Re: Autonomic cardiovascular regulation in quiescent ulcerative colitis and Croh

[Guest guest]

The autonomic nervous system controls systems that not under typical

conscious control like the heart rate (via the vagus nerve), arterial

wall smooth muscle tone, sweating, salivation etc. If the autonomic

nervous system of your heart and blood pressure is weak then you get

light headed when standing because the heart rate wouldn't increase

enough and the arteries wouldn't tighten to maintain blood pressure.

Incidently this happens to astronauts. When they are in space their

loose autonomic tone and are lightheaded when they return to earth

until they get back in shape.

A resting heart rate of 50 at rest can mean good cardiovasuclar

conditioning because at rest the heart can deliver plenty of blood at

a low pumping rate. PVCs can be more common at lower heart rates but

is probably not directly related to sympathetic tone.

Why this would be different in UC compared to CD is over my head. I

don't know how the investigators could control for overall fitness.

Humm, maybe I should read the article.

Von

>

> =============

> Autonomic cardiovascular regulation in quiescent ulcerative colitis

and Crohn's disease

>

> ...Cardiac vagal control is impaired in quiescent ulcerative colitis

only, and not in Crohn's disease, while in both bowel diseases

vascular control appears preserved. Since cardiovagal modulation seems

related to anti-inflammatory mechanisms, the reduced parasympathetic

cardiac regulation in apparently quiescent ulcerative colitis suggests

that such systemic derangement is accompanied by local subclinical

inflammations, even in the absence of clinically active inflammatory

processes.

>

> Eur J Clin Invest 2007; 37 (12): 964-970

>