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Hi All,

I want to reintroduce myself, it has been years since I have

posted on this board, but drop into read the post often.

I am 36 years old, I was diagnosed with UC in 2000, PSC in 2001. I

had a wonderful pregnancy in 2002. My colitis was put into

remission in 2001, and had been in remission until the last 2 years.

My PSC has been unremarkable, labs were up and down, but have been

consistently low for a while. I have always had a little URQ

discomfort, but in October, it became much more consistent and

intense. My GI ran the normal test put me back on prednisone for my

UC, and found that I have a blockage of my portal vein, they found a

small dark area in my liver. The liver biopsy of the area came back

inconclusive. So on to the Cleveland Clinic, for more test, I have an

ERCP scheduled later this month, I am really hoping for some relief

and answers to what is going on.

Can anyone shed some light on the causes of PSC pain? I know that

mine is different because of portal veinblockage, but what is the

general reasoning, if bile duct blockage is not the problem.

Jenn

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I'm not sure what happens but I was told by one doctor (can't remember

which one) about something called viseral hypersensitivity, which

means that the sac around the liver could be more sensitive or

something and when the liver is enlarged it can cause pain. I know

that my liver and spleen are both enlarged and think that's what

causes a lot of my pain. Especially after I eat because then my

stomach expands and puts even more pressure on the area.

Gosh I hope that makes sense, lol.

PSC 8/07

PBC 10/06

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