Guest guest Posted January 17, 2008 Report Share Posted January 17, 2008 Hi all!!! I know that I am not around here a lot. As of last November I started getting some strange symptoms, I started having night sweats, fever of appox 100, caughing, loss of appetite etc. So my GI sent me to have a CT Scan turns out that I had enlarged lymph nodes. Subsequently my GI sent me to a Hematologist/ Oncolologist as he was afraid that it was NH Lymphoma. The HO sent me for a Pet Scan which showed lymph nodes lighting up, and a mass at the in my chest. I just had a full (not fine needly) biopsy on my chest and one lymph node in my belly. The results were - HYPERPLASIA and not lymphoma. Would anyone know what that is and how that would be treated. I know it is not directly related to PSC CD or UC but from what I know it is related to the autoimmune system. Thanks in advance!! Shaul PSC UC (For a long time) mid 90'sStart the year off right. Easy ways to stay in shape in the new year. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 17, 2008 Report Share Posted January 17, 2008 Hi Shaul; The only 'encounter' I have had with lymphoid hyperplasia was when my son (, with PSC and UC) was found to have an area of lymphoid hyperplasia in his terminal ileum during his colonoscopy about 18 months ago. We were told that it was nothing to worry about ... but I was concerned. Fortunately, during his last colonoscopy (about 1 month ago), the terminal ileum now looked normal! I can't explain why/how this occurred. One cause of enlarged lymph nodes (non-malignant hyperplasia) could be Castleman's disease. A few links are provided below: ICDO - International Castlemans Disease Organization http://www.castlemans.org/ Castleman's disease (Wikipedia) http://en.wikipedia.org/wiki/Castleman's_disease Castleman's disease (Mayo Clinic) http://www.mayoclinic.com/health/castleman-disease/DS01000 Some forms of the disease seem to be caused by viruses, and others by hyperproliferation of B cells that produce inflammatory cytokines like interleukin-6. The former has been treated with anti-viral agents, and the latter with a new B cell antibody called rituximab. A case report is described in this paper ... here steroid therapy induced remission: http://www.jmedicalcasereports.com/content/1/1/78 I hope that this information helps, and that the biopsy specimens will help choose the right treatment. The complications of PSC and IBD never cease to amaze me. Best regards, Dave (father of (22); PSC 07/03; UC 08/03) Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 21, 2008 Report Share Posted January 21, 2008 Dave:Thanks for the insite. Greatly appreciated! Shaul UC PSCStart the year off right. Easy ways to stay in shape in the new year. Quote Link to comment Share on other sites More sharing options...
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