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Medications and the liver

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Almost every chemical you consume is ultimately processed by the liver or the kidneys. Ibuprofen through the kidneys; Tylenol, toradol, alcohol, many chemicals through the liver. PSC puts stress on the kidneys, because they try to compensate for the liver's ineffectiveness (hence cola-colored urine, sometimes).

If you have high cholesterol and PSC (many do), do you take Lipitor, which is hard on the liver? Some do, on doctor's orders. I was once given toradol (processed by the liver) during a cholangitis episode, because they were concerned about the effect of other painkillers on my (single) kidney. I was far more concerned about my liver.

Nothing is 100% safe, everything is a balancing act, there are no absolute answers. That's one reason that medical training takes so many years.

Arne

56 - UC 1977, PSC 2000

Alive and (mostly) well in Minnesota

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This is for me one of the frustrating facts for people with PSC. If I

have an ache or pain, my PSC doctor says NO tylenol, my hematoligist

says NO aspirin and both of my gastros (for crohns) say NO Ibuprofin,

so it really doesn't leave me with very many options for pain. But of

course each doctor says that it's ok to take one of the other pain meds

but under no circumstances take the one that THEY don't want me on.

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This is for me one of the frustrating facts for people with PSC. If I

have an ache or pain, my PSC doctor says NO tylenol, my hematoligist

says NO aspirin and both of my gastros (for crohns) say NO Ibuprofin,

so it really doesn't leave me with very many options for pain. But of

course each doctor says that it's ok to take one of the other pain meds

but under no circumstances take the one that THEY don't want me on.

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