Use of coronary stent in hepatic artery stenosis after LTX

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The use of coronary stent in hepatic

artery stenosis after orthotopic liver

transplantation

Mingsheng Huang, Hong Shan, Zaibo

Jiang, Zhengran Li, Kangshun Zhu, Shouhai Guan, Jiesheng Qian, Guihua Chen, Minqiang Lu and Yang

Yang Department of Radiology, Guangdong Province, China

Abstract

Purpose

This

retrospective study was undertaken to evaluate the effectiveness of coronary

stent placement in hepatic artery stenosis after orthotopic

liver transplantation (OLT).

Materials

and methods

Of 430

consecutive adult orthotopic liver transplant

recipients between November 2003 and September 2005, 17 had hepatic artery

stenosis (HAS). Fourteen of them underwent coronary

stent placement in the HAS. The technical results,

complications, hepatic artery patency

and clinical outcome were reviewed.

Results

Technical

and immediate success was 100%. After a mean follow-up

of 159.4 days (range, 9–375 days), all patients obtained patent hepatic

arteries except 2 patients occurred hepatic artery restenoses

at 26 and 45 days after stent placement, respectively. Kaplan–Meier

curve of patency showed cumulated stent patency at 3, 6, and 12 months of 78%, 58% and 45%,

respectively. During the follow-up, 8 patients

survived, 5 died of septic multiple-organ failure, 1 received retransplantation because of refractory biliary infection. Hepatic artery dissection induced by a guiding catheter

occurred in one patient and was successfully treated with a coronary stent.

Conclusion

Hepatic

artery stenosis after OLT can be successfully treated with coronary stent

placement with low complication rate and an acceptable 1-year hepatic artery patency rate.