Re: antibiotics

[Guest guest]

(ost tx 2 years) called from college yesterday with symptoms of what I thought was strep. I called his team and they said he definitely should go to the ER for a swab. His Dr also said if he tested positive to never get put on Erythromyacin, Biaxin or a Z-pac. She said they up the prograf level so high in the blood it can put you in kidney failure very fast. This was the first I heard of this. Is this what your Drs are saying? MartiMO425@... wrote: Barb, I will see what I can do. Thanks for the heads up! (MO)

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[Guest guest]

All these antibiotics share the same metabolic pathway used by

tacrolimus and cyclosporine, and if used together would require

recalibrating the dose of immunosuppressant required to achive the

desired blood level. Not something you'd want to do for a 1 or 2

week course of antibiotics.

My doctor also nixed using augmentin, I believe because of the Joint

Formulary Committee's report in the British National Formulary, 47th

edition (2004) that " [augmentin] has been associated with an

increased incidence of cholestatic jaundice and acute hepatitis

during therapy or shortly after, particularly in men and those aged

over 65 years. The associated jaundice is usually self-limiting and

very rarely fatal. " Now I'm not yet 65, but would hate to be one of

the rare cases where the jaundice was fatal.

Tim R

>

> (post tx 2 years) called from college yesterday with

symptoms of what I thought was strep. ... His Dr also said if he

tested positive to never get put on Erythromyacin, Biaxin or a Z-

pac. She said they up the prograf level so high in the blood it can

put you in kidney failure very fast. ... Is this what your Drs are

saying?

> Marti