Guest guest Posted March 9, 2007 Report Share Posted March 9, 2007 ED is probably more common than is known for men with PSC. I doubt most doctors, GI and Hepatologists, ask about it. But the liver is involved in metabolism of hormones and chronic liver disease is known to affect testosterone metabolism. In addition, chronic liver disease is males affects testicular function, again leading to decreased testosterone levels. Combined with the fatigue of chronic liver disease sexual performance can tank. As mentioned, none of the erectile dysfunction drugs are safe for anyone with varices. And since testosterone may increase liver damage it's probably not safe either. As a side note, your husband should be having regular once at least and perhaps more often, upper endoscopies to look at his varices. At that time any larger ones can be banded to prevent bleeding. If he's taking a beta-blocker for prevention of variceal enlargement, these kinds of drugs are known to cause ED and sexual performance issues. The best news is that all of this will resolve after transplant. Aubrey, MD PSC '81, UC '90, LTX '98, Recurrence '05 Quote Link to comment Share on other sites More sharing options...
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