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Celebrex and PSC

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While Celebrex is known to cause liver inflammation in some of the

people who take it, I have never seen a report of it causing PSC. I

review drugs and adverse drug reactions for Health Canada, our version

of the FDA. NSAISs and COX-2 inhibitors are some of the drugs that I

review regularly. I don't think there is a connection between the two.

I was on NSAIDs for years after being diagnosed with liver disease, for

my arthritis, and except for nearly bleeding to death (twice), I don't

think it affected my liver disease. Perhaps I was lucky.

Aubrey, MD

PSC '81, UC '90, LTX '98, Recurrence '05

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