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My doctor has asked me to read info on methotrexate and humira for my

crohn's. Apparently I have become steroid dependent and the remicade

infusions did not work for me. Can anybody give me some insight who

has tried these drugs? I'm specifically looking for side effects and

how it effected your PSC. The methotrexate seems to give strong

warnings about liver damage. Any feedback would be great.

Thanks,

Cheryl

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I have been taking Humira injections for about 2 months. I take them every two

weeks. Works great and I have not had any side effects. It takes a little

getting use to because you give yourself the injections but other than that - it

has worked as well as the Remicade for me.

PSC '01

Crohn's

>>> " cheryl Zahajko " 5/28/2007 10:07 AM >>>

My doctor has asked me to read info on methotrexate and humira for my

crohn's. Apparently I have become steroid dependent and the remicade

infusions did not work for me. Can anybody give me some insight who

has tried these drugs? I'm specifically looking for side effects and

how it effected your PSC. The methotrexate seems to give strong

warnings about liver damage. Any feedback would be great.

Thanks,

Cheryl

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HI Cheryl,

I have a severe case of Psoriatic Arthritis (PsA) involving most of my joints and cartilage. I take one injection of Humira weekly. This drug has helped me immensely!

Before Humira, I had large ugly, red , scaling sores all over my body, scalp, arms, legs, etc. Now they are fading. Before Humira, I had to take Hyrocodone to control the joint pain and pain caused from the connective tissue swelling. My range of motion was severely impaired. I am moving much better now - slowly, but better. Not walking like "enstein" anymore.

Humira has been recommended for crohns as well as PsA. It sure works well for me! The injections (I give to myself) lasts about 10 seconds and is painful (like a bee or wasp sting). But that is nothing compared to the constant pain of PsA! I have fatty liver (my liver enzymes are twice what they should be - but they are coming down now with Humira)

The main side effect is the cost ($30,000 per year for weekely injections, and not all insurance companies will pay. Thankfully mine does), and the stinging duing injection for about 10 seconds). I have had no other untoward side effects.

My doctor never recommended Methotrexate to me, I think Humira was the drug of choice here given the severity of symptoms. Stress makes the symptoms worse. We had had tried Mobic, prednisone, Plaquenil, cyclobenzeprine, atarax, and Tramadol and nothing seemed to help except Humira! To me this a miracle drug!

Chris

medication questions

My doctor has asked me to read info on methotrexate and humira for my crohn's. Apparently I have become steroid dependent and the remicade infusions did not work for me. Can anybody give me some insight who has tried these drugs? I'm specifically looking for side effects and how it effected your PSC. The methotrexate seems to give strong warnings about liver damage. Any feedback would be great.Thanks,Cheryl

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