Re: What's new for 'vulvodynia' in pubmed

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, thanks for the article.... ~Chelle Gunn wrote: Zawislak AA, McCarron PA, McCluggage WG, Donnelly RF, Price JH, McClelland HR, Woolfson AD. Department of Gynaecology, Belfast City Hospital; School of Pharmacy, Queen's University Belfast, UK. OBJECTIVE: To assess the applicability of photodynamic therapy (PDT) in the management of vulvodynia whereby a

novel, patch-type system, loaded with 5-aminolevulinic acid (ALA), was used to administer PDT to vulvar regions displaying the characteristics of vulvodynia. STUDY DESIGN: Eleven patients underwent PDT using a bioadhesive patch to deliver ALA over 4 hours. A nonlaser light source delivered 100 J cm(-2) to the target area using red light of 630 nm. Fluorescence of protoporphyrin IX was observed under ultraviolet light illumination, with no significant difference found between that produced after the first and second applications of the patch. RESULTS: There was a significant reduction (p= 0.0077) in overall symptoms after completion of treatment. No significant alleviation (p = 0.1088) in pain during intercourse was observed following treatment. Eight patients experienced a symptomatic response, while 3 exhibited no improvements in symptoms. No adverse reactions or worsening of reported symptoms was reported. CONCLUSION: The results suggest that PDT is of value in the

management of vulvodynia, most probably as a viable option to conventional approaches. Further studies involving larger numbers of patients are required to confirm the efficacy of PDT in the management of vulvodynia. PMID: 17847765 [PubMed - in process]

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My NCBI wrote: This message contains My NCBI what's new results from the National Center for Biotechnology Information (NCBI) at the U.S. National Library of Medicine (NLM).Do not reply directly to this message. Sender's message: Search: vulvodyniaSent on Saturday, 2008 Mar 29Search vulvodyniaClick here to view complete results in pubmed. (Results may change over time.)