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Re: information from the Conference for Carolyn B.

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Hi, Carolyn!! I wish you'd been at the conference - it was very

science-intensive, and I think you would've loved it. One of the most

interesting things that they mentioned was that they are exploring the

autoimmune nature of PSC - they are changing their view of it from a

classic autoimmune disease to something they called an

autoimmune " disregulation. " I'm sure someone who went farther in

science than I did can step in and explain it further, but it seemed

to me they were getting quite close to explaining how the combination

of a genetic susceptibility and environmental trigger could create a

self-perpetuating cycle of " disregulated " immune cells that, if I

recall correctly, somehow left the chloride channels of the biliary

tract cells producing an excess of certain chemicals and deficit of

others. Wow, reading this over again it is clear that I really am bad

at science - does anyone else who actually understood this stuff want

to speak up? tx,

Nina in Philly

>I'd like to hear some of the information from the

> conference. (By information, I mean the real stuff .... not

quarreling

> over the use of adjectives.)

>

> Carolyn B. in SC

>

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