Re: ERCP confirms PSC/Jed

[Guest guest]

Most hepatologists prescribe Ursodiol for PSC; typically in the 20-30 mg/kg

dosage. The studies on urso are conflicting as to benefit, with the exception

that it appears to provide some colon cancer protection (for which PSCers are at

increase risk). It may delay the time to transplantation, as it clearly does

improve liver chemistry. It IS a benefit to PBC patients.

The rest of the regimen is consistent with most hepatologist's recommendations.

There are studies that show benefit from milk thistle (see

http://www.psc-literature.org/scilit.htm under Milk Thistle), and some that

don't. I take milk thistle and SAMe (see above source, under SAMe) - both AFTER

my hep OK'd it.

Most people with PSC do better with low fat, low (animal) protein diets.

Minimal or no alcohol is also usually recommended. If you have UC or Crohn's,

it's pretty important to pay attention to diet, as you may not absorb sufficient

nutrients otherwise. See Nutrition and Diet under the above source for more

info.

Arne

---- Jed wrote:

=============

....The hardest part was hearing that there is nothing he wants to presecribe

right now. Usually you go to the doctor and they give you something

to fix your problem...

The plan right now is for me to get hepatitis vaccines next week,

then see him in 6 months for a bone density scan/checkup. And also do

colon cancer testing once per year.

I was also wondering are there any diet changes/supplements which can

help your liver?...

[Guest guest]

Jed,

I'm on a very low dose URSO, 500mg a day, about 5 mg/kg/day. I consider it more an additive (imitation Bear bile) and for me I have no side effects. For the first tens years of my disease I wasn't on anything but my liver enzymes slowly rose, but for the last eight years I have been on Ursodiol and have better Liver enzyme readings than in the first ten years.

Ian Cribb PSC (89)

Most hepatologists prescribe Ursodiol for PSC; typically in the 20-30 mg/kg dosage. The studies on urso are conflicting as to benefit, with the exception that it appears to provide some colon cancer protection (for which PSCers are at increase risk). It may delay the time to transplantation, as it clearly does improve liver chemistry. It IS a benefit to PBC patients.

The rest of the regimen is consistent with most hepatologist's recommendations.There are studies that show benefit from milk thistle (see

http://www.psc-literature.org/scilit.htm under Milk Thistle), and some that don't. I take milk thistle and SAMe (see above source, under SAMe) - both AFTER my hep OK'd it.Most people with PSC do better with low fat, low (animal) protein diets. Minimal or no alcohol is also usually recommended. If you have UC or Crohn's, it's pretty important to pay attention to diet, as you may not absorb sufficient nutrients otherwise. See Nutrition and Diet under the above source for more info.

Arne---- Jed wrote: =============...The hardest part was hearing that there is nothing he wants to presecribe right now. Usually you go to the doctor and they give you something to fix your problem...The plan right now is for me to get hepatitis vaccines next week, then see him in 6 months for a bone density scan/checkup. And also do colon cancer testing once per year.I was also wondering are there any diet changes/supplements which can help your liver?... -- Ian Cribb P.Eng.