Severe Psychiatric Problems in Right Hepatic Lobe Donors for LDLT.

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Severe Psychiatric Problems in Right Hepatic

Lobe Donors for Living Donor Liver Transplantation.

Brief Reports

Transplantation. 83(11):1506-1508, June 15, 2007.

Trotter, F. 1,9; Hill-Callahan,

Margaret M. 2; Gillespie, W. 3; Nielsen, A. 4; Saab, Sammy 5; Shrestha, Roshan 6; Talamantes, M. 7; Weinrieb,

M. 8; the A2ALL Study Group

Abstract:

Background. The morbidity and mortality from donation

of a right hepatic lobe for living donor liver transplantation (LDLT) is an

important issue for this procedure. We report the

prevalence of severe psychiatric postoperative complications from the

Adult-to-Adult Living Donor Liver Transplantation Cohort study (A2ALL), which

was established to define the risks and benefits of LDLT for donors and

recipients.

Methods. Severe

psychiatric complications were evaluated in all donors from the A2ALL study who

were evaluated between 1998 and February 2003.

Results. Of

the 392 donors, 16 (4.1%) had one or multiple psychiatric complications,

including three severe psychiatric complications (suicide, accidental drug

overdose, and suicide attempt).

Conclusions. Despite

extensive preoperative screening, some donors experience severe psychiatric

complications, including suicide, after liver donation. Psychiatric

assessment and monitoring of liver donors may help to understand and prevent

such tragic events. © 2007 Lippincott & Wilkins, Inc.

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