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Re:Pancreatitis

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Sorry to hear your son developed pancreatitis after having an ERCP and

stent placement. I hope the removal goes a bit better. Cirrhosis is a

diagnosis that can only be made via biopsy as it's a pathological

diagnosis based, by definition, on bridging necrosis that is seen on

looking at the biopsy tissue under a microscope. As mentioned, you can

see it in some tissue samples and not in others. So it depends on how

good the biopsy is and where they take it from in the liver. Since the

liver regenerates the biopsy can miss areas of damage that would lead

to a diagnosis of cirrhosis. I've had 8 liver biopsies. Or nine. Can't

remember exactly. The first one I had showed cirrhosis about a year

into my disease symptoms. And yet it took 18 years before my liver

packed it in and I required a tx. So you never know the exact

significance of saying there is cirrhosis. More important is how the

liver is functioning. And the tests for that are INR and serum albumin.

If they are normal, the liver is functioning well despite the disease.

Aubrey, MD

PSC '81, UC '90, LTX '98, Recurrence '05

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Sorry to hear your son developed pancreatitis after having an ERCP and

stent placement. I hope the removal goes a bit better. Cirrhosis is a

diagnosis that can only be made via biopsy as it's a pathological

diagnosis based, by definition, on bridging necrosis that is seen on

looking at the biopsy tissue under a microscope. As mentioned, you can

see it in some tissue samples and not in others. So it depends on how

good the biopsy is and where they take it from in the liver. Since the

liver regenerates the biopsy can miss areas of damage that would lead

to a diagnosis of cirrhosis. I've had 8 liver biopsies. Or nine. Can't

remember exactly. The first one I had showed cirrhosis about a year

into my disease symptoms. And yet it took 18 years before my liver

packed it in and I required a tx. So you never know the exact

significance of saying there is cirrhosis. More important is how the

liver is functioning. And the tests for that are INR and serum albumin.

If they are normal, the liver is functioning well despite the disease.

Aubrey, MD

PSC '81, UC '90, LTX '98, Recurrence '05

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