RE; Another comtan question?

[Guest guest]

Vera,

I'm not sure what Mirapex is. Comtan is supposed to boost the effects of sinemet, as I understand it. For me, it lessens the severity of leg spasms but not even that entirely.

Barbara

[Guest guest]

Is comtan ,something like mirapex or would it be different?

Thanks

Vera

[Guest guest]

Vera,

Comtan is a COMT inhibitor and I think Mirapex is a dopamine agonist, so they

work in different ways. Comtan helps the L-dopa get into the system faster

and Mirapex tends to keep it in the system longer. Comtan does no good

unless taken with Sinemet where Mirapex can help by itself. I think ) My

PD site is not working tonight.

Hugs Bill

I got hugs from Terri and Grammy Rose today, and was there too.

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FVJAMES@... wrote:

> Is comtan ,something like mirapex or would it be different?

>

> Thanks

> Vera

>

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[Guest guest]

We were told that Comtan would extend the effects of Sinemet and cut down on

Ken's off time when he became very rigid. he was taking Sinemet CR which had

helped that some, but he still had a lot of rigidity. Whenever we tried to

give him more Sinemet to help with this, he would become more disoriented and

his BP would fall even faster. he had a top amount of Sinemet he could

tolerate of about 600 mg per day spread out. He was on this amount for over

15 years, and he really needed more. The Comtan didn't seem to have the side

effects that extra Sinemet had. He tried Mirapex also, but the side effects

were even worse than more Sinemet. We knew the Comtan was helpful when Ken

got up from his chair on one bounce and walked alone across the room and fell

and cut his forehead! Prior to that he had been unable to get up without

bouncing three or four times giving one of us time to get to him and stand

beside him when he walked. We considered this particular fall evidence that

Comtan was working well! Also, Tasmar is like Comtan but works better for

some. The problem is that you must have frequent blood tests of liver

function if you are taking Tasmar because some have died from liver troubles

with Tasmar. This might be a risk worth taking to gain more mobility. I know

several people who take Tasmar and think the risk is worth it.

Barbara