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Cortisol - side effects?

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Hi all,

I just started Cortisol (5 mg hydrocortisone), that is time-released,

3 days ago. It has made me incredibly insomniac, and it is such a low

dose! I also feel really nauseous from it and a bit anxious. Anyone

else experience bad reactions to cortisol, even on such a low dose?

And if so, did trying a lower dose help you, or did you try Isocort?

ANY help is appreciated. My doctor is being a jerk in terms of not

responding to me.

Background:

The reason I am starting this is for low adrenals (confirmed by an ASI

saliva test as well as symptoms). I was daignosed with hypothyroidism

back in July 2007, and tried Unithroid (t4) at the lowest dose. After

3 weeks of awful dizziness and migraines on it, I started developing

horrible anxiety/insomnia/hyper like symptoms - even on the lowest dose!

I then tried Armour a few months later, and after 4 days my heart

pounded so hard and painfully I thought I was having a heart attack.

I am no longer on thyroid meds, not until my body gets some cortisol

or adrenal healing going. My doc tells me my adrenals are part of the

reason for my inability to tolerate thyroid meds. Anyways, I want to

know if anyone else has solutions to this seemingly inability to

tolerate cortisol. I feel like I can't tolerate anything! My body is

hypo and low adrenal and yet I cannot take the medicines!

I feel so helpless and sad. I have taken medical leave 2 months ago

because I am unable to work, or pretty much do anything, including

leaving the house for extended periods of time b/c of exhaustion,

lightheadedness, brain fog, depression, etc.

Thanks for your help.

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When are you getting the nausea? In relation to when you take the dose?

Is it just ONE dose or do you dose several time s a day? Too low a dose

can cause these symptms if your body is really lwo on cortisl.

--

Artistic Grooming- Hurricane WV

http://www.stopthethyroidmadness.com/

http://health.groups.yahoo.com/group/NaturalThyroidHormonesADRENALS/

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I don't know what to tell you as far as your reactions to cortisol. I am not

familiar with the time released and you are on a very low dose. You didn't

say how many times a day you take it and in what time blocks?

You might try cream and see if you have the same reactions at the same dose.

It may be a dosing issue or something in the time released you are reacting

to.

Do you have your old labs to share? Thyroid, cortisol, DHEA? It is much

easier to advise when we can see some labs along with symptoms.

Not tolerating thyroid meds due to adrenal issues is very common on this

list. I seem to be one of them.

Cheri

-----Original Message-----

I feel so helpless and sad. I have taken medical leave 2 months ago

because I am unable to work, or pretty much do anything, including

leaving the house for extended periods of time b/c of exhaustion,

lightheadedness, brain fog, depression, etc.

Thanks for your help.

.

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Really? Too low dose can cause insomnia?

I take 5 mg of a time-released hydrocortisone (compunded for me, with

no synthetic fillers) in the morning. Just once. I was sleeping just

fine before - about 11-13 hours a night, and then immediately after I

started the cortisol, I became insomniac again immediately. That is

the most bothersome symptom, since my adrenals need to rest during

sleep and now I'm not getting any sleep. Now I slept 3-4 real hours

last night and feel totally out of whack and exhausted and crazy again.

The nausea usually hits in the afternoon.

I just left my doc a message that I want to try about 1/4 of this dose

to slowly go up on it. And I also asked if he could take me off the

time-released dose (in case that is what's hitting me in the evening

and causing my insomnia). I am INCREDIBLY sensitive to all things, so

I am not surprised even 5 mg is affecting me negatively.

Not sure if I really need cortisol, or if my body just needs a lower dose.

>

> When are you getting the nausea? In relation to when you take the dose?

> Is it just ONE dose or do you dose several time s a day? Too low a dose

> can cause these symptms if your body is really lwo on cortisl.

>

> --

> Artistic Grooming- Hurricane WV

>

> http://www.stopthethyroidmadness.com/

> http://health.groups.yahoo.com/group/NaturalThyroidHormonesADRENALS/

>

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If your doigestion is bacd it could be that it is not hitting you intul

WAY later than it should. Thsi is one of my huge things I disliek abotu

slow released hormones. it is a guessing game as to how slow or fast you

really are getting them and with a time dependent dosing as HC can be..

not ogod.

--

Artistic Grooming- Hurricane WV

http://www.stopthethyroidmadness.com/

http://health.groups.yahoo.com/group/NaturalThyroidHormonesADRENALS/

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Yes, too low a dose and too infrequent. Yes, it can lower further because

once you start taking cortisol you start impacting the HPA axis which also

controls sleep. Once you get up to your needed dose, sleeping should

improve. For me it took 35 mg and now I am down to 30 mg.

The nausea hits in the afternoon because you are too low in the morning and

throw it off for the rest of the day. Cheri

Re: Cortisol - side effects?

Really? Too low dose can cause insomnia?

I take 5 mg of a time-released hydrocortisone (compunded for me, with

no synthetic fillers) in the morning. Just once. I was sleeping just

fine before - about 11-13 hours a night, and then immediately after I

started the cortisol, I became insomniac again immediately. That is

the most bothersome symptom, since my adrenals need to rest during

sleep and now I'm not getting any sleep. Now I slept 3-4 real hours

last night and feel totally out of whack and exhausted and crazy again.

.

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Hi,

Just to clarify, I only took ONE 5 mg tablet daily. It was time

released, so it time-releases on its own (I guess) throughout the

whole day. With such a low dose, I would imagine I would be fine but

my insomnia was horrible during those 3 days I was on it. I stopped

taking it yesterday.

Here are the results from my JUNE 2007 ASI saliva tests:

Free Cortisol Ryhthm:

7-8 am 5 (depressed), Range 13=24 nM

11-12 noon 5 (depressed), Range 5-10 nM

4-5 pm 8 (normal/high?), Range 3-8 nM

11- Midnight 2 (normal), Range 1-4 nM

Cortisol Burden was 17 (range 23-42)

Progesterone was 22 (normal) with optimal at 22 - 100 pg/ML and

elevated >130 pg/mL

DHEA was Normal at 5 (3-10 ng/mL).

However, the doctor treating me now is treating me for LOW cortisol

(based on symptoms and a JUNE 2007 test). Shouldnt he REtest, as it is

now January 2008? Although I feel low cortisol with all my symptoms,

and have been unable to tolerate thyroid meds, I still feel he should

retest to make sure my levels are low.

Again, I feel the symptoms of adrenalfatigue, but there are times when

I have bad insomnia (which I would imagine means excess cortisol)?

Any thoughts would be helpful.

>

> I don't know what to tell you as far as your reactions to cortisol.

I am not

> familiar with the time released and you are on a very low dose. You

didn't

> say how many times a day you take it and in what time blocks?

>

> You might try cream and see if you have the same reactions at the

same dose.

> It may be a dosing issue or something in the time released you are

reacting

> to.

>

> Do you have your old labs to share? Thyroid, cortisol, DHEA? It is much

> easier to advise when we can see some labs along with symptoms.

>

> Not tolerating thyroid meds due to adrenal issues is very common on this

> list. I seem to be one of them.

>

> Cheri

>

>

> -----Original Message-----

>

>

>

> I feel so helpless and sad. I have taken medical leave 2 months ago

> because I am unable to work, or pretty much do anything, including

> leaving the house for extended periods of time b/c of exhaustion,

> lightheadedness, brain fog, depression, etc.

>

> Thanks for your help.

>

> .

>

>

>

>

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What that ONE 5MG did for you was lower your ACTh later in the day where

LOW cortiosl is what disturbed your sleep probably mixed with

hypoglycemia which goes with it. Thsi si not a side effect, btu a normal

effect of taking too low a dose.

--

Artistic Grooming- Hurricane WV

http://www.stopthethyroidmadness.com/

http://health.groups.yahoo.com/group/NaturalThyroidHormonesADRENALS/

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You have low cortisol in June tests and I don't know exactly how the doc was

treating you but 5mg once a day is not helping. It is probably making it

worse. I am not sure what the goal of the doctor was but you need cortisol

in your morning (which should be highest) and the early noon. 5 mg is not

enough to bring a 5 level up high enough, which messes you up for the rest

of the day (and night). The reason you are having low cortisol symptoms is

because you are still low and the low dose he has you on is not helping.

That is also why you can't tolerate thyroid meds.

In order to retest you have to be off cortisol for 2 weeks to get an

accurate measure.

To put it in perspective, I started cortisol in October and by January was

up to 35 mg before I got any real results.

Cheri

-----Original Message-----

Hi,

Just to clarify, I only took ONE 5 mg tablet daily. It was time

released, so it time-releases on its own (I guess) throughout the

whole day. With such a low dose, I would imagine I would be fine but

my insomnia was horrible during those 3 days I was on it. I stopped

taking it yesterday.

However, the doctor treating me now is treating me for LOW cortisol

(based on symptoms and a JUNE 2007 test). Shouldnt he REtest, as it is

now January 2008? Although I feel low cortisol with all my symptoms,

and have been unable to tolerate thyroid meds, I still feel he should

retest to make sure my levels are low.

Again, I feel the symptoms of adrenalfatigue, but there are times when

I have bad insomnia (which I would imagine means excess cortisol)?

Any thoughts would be helpful.

.

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You're saying that taking too LOW a dose of cortisol would give me

insomnia? This just doesn't feel right, because the other thing

besides insomnia i got from just 3 days of cortisol (5 mg only/daily)

was anxiety, a slight raciness in my heart feeling, etc. Now that I've

been off cortisol for three days, my insomnia is persistent and still

AWFUL. I took 2 melatonin and an Ambien last night and could only

sleep 4 hours and I'm an emotional and physical mess.

I'm INCREDIBLY sensitive to all meds and wonder if cortisol just

doesn't agree with some body types, and if I'd be better to take

licorice or Isocort.

Any thoughts?

>

> What that ONE 5MG did for you was lower your ACTh later in the day

where

> LOW cortiosl is what disturbed your sleep probably mixed with

> hypoglycemia which goes with it. Thsi si not a side effect, btu a

normal

> effect of taking too low a dose.

>

> --

> Artistic Grooming- Hurricane WV

>

> http://www.stopthethyroidmadness.com/

> http://health.groups.yahoo.com/group/NaturalThyroidHormonesADRENALS/

>

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Share on other sites

You're saying that taking too LOW a dose of cortisol would give me

insomnia? This just doesn't feel right, because the other thing

besides insomnia i got from just 3 days of cortisol (5 mg only/daily)

was anxiety, a slight raciness in my heart feeling, etc. Now that I've

been off cortisol for three days, my insomnia is persistent and still

AWFUL. I took 2 melatonin and an Ambien last night and could only

sleep 4 hours and I'm an emotional and physical mess.

I'm INCREDIBLY sensitive to all meds and wonder if cortisol just

doesn't agree with some body types, and if I'd be better to take

licorice or Isocort.

Any thoughts?

>

> What that ONE 5MG did for you was lower your ACTh later in the day

where

> LOW cortiosl is what disturbed your sleep probably mixed with

> hypoglycemia which goes with it. Thsi si not a side effect, btu a

normal

> effect of taking too low a dose.

>

> --

> Artistic Grooming- Hurricane WV

>

> http://www.stopthethyroidmadness.com/

> http://health.groups.yahoo.com/group/NaturalThyroidHormonesADRENALS/

>

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