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Wow, I have had Rheumatoid Arthritis (an auto-immune disease) for 25

years. Interesting thought. What made you wonder that?

Homekeeper

> >

> > I have been suffering for nearly two years with Adrenal Exhaustion,

> > anxiety and a few panic attacks. I'm on Armour Thyroid and

> > bio-identical hormones, too. I have a small goiter with cysts, which

> > have barely grown in two years, according to the recent ultrasound.

> >

> > I'm looking so forward to March when I first see a hopefully, good

> > doctor that not only uses Armour Thyroid but does saliva testing!!

> > and, I've heard, understands Adrenal Exhaustion.

> >

> > In the meantime, I went to a licensed nutritionalist (which has a

> lot

> > of medical school training) and does muscle testing too for what

> > supplements your body needs. I believe she is on to something

> > interesting that no other doctor mentioned.....

> >

> > She said it may be my hypothalimus-pituitary axis that is damaged or

> > unbalanced and to take phosphitidal serine (PS). I put the cream on

> > the third eye (middle of forehead where it gets absorbed and can

> even

> > avert a possible panic attack. Also, I've been taking two capsules

> > with breakfast.

> >

> > Here's the interesting part: My husband and I just came back from

> > watching our 5 month old teething grandson that I had to feed every

> > 2-3 hours around the clock. We also watched his three year old

> > brother that, though loving, shall we say, is THE MOST defiant,

> > trying, manipulative child, ever!!! You can not imagine the physical

> > and emotional turmoil we were in for 8 days! Before we left I

> thought

> > I'd end up in bed the whole time taking care of the baby, come home

> > and die. WELL------- as soon as I started watching the kids I went

> > into what my husband called, " Mommy Mode. " I went like the Eveready

> > Bunny the whole time, mostly full of energy, just doing what had to

> be

> > done. Before we left I could only function for four or five hours in

> > the morning. The rest of the time I was 'couch sitting.' I've been

> > home for six days and now I'm starting to tire, but not like before

> we

> > left.

> >

> > The day after we came home I went to my nutritionalist and she said

> > though I still need my hormones and thyroid balanced and have

> Adrenal

> > Fatigue, because of when I focus, I'm so much better she thought

> part

> > of my problem might be my hypothalimus-pituitary axis.

> >

> > The first time I saw her I told her the only time I felt good

> > (emotionally and physically) was when I played darts for a few

> minutes

> > with my husband. Before I did, I could barely move because I was so

> > physically wiped out, not from

> > doing anything physical. After a minute or two of playing darts

> > (which I'm not particularly fond of) I felt soooooo much better.

> This

> > is what made her think there MAY be a need for PS. After the

> > grandchildren experience, she really believes my

> > hypothalimus-pituitary axis is the greater problem. Possibly from a

> > past sinus infection or candida got up there.

> >

> > I'm still taking my PS, orally and topically and taking Lion's Mane,

> > Nerve Factors. I'm also now taking Caprilic Acid gelcaps and

> Oregamax

> > to knock out the candida/fungus. She also wants me to focus on a

> > flame a few times a

> > day and do to cross-stitch or some other type of needlework. Ha, and

> > to keep playing darts.

> >

> > It is just amazing the world of difference since I went to watch my

> > grandchildren. Before I didn't ever think I would heal my AF, since

> > it was not improving and so, mentally, I was worsening. Now, I'm so

> > much better. Still in need of balancing my other physical problems,

> > hopefully, with a knowledgeable doctor next month. But, in the

> > meantime, and since I haven't seen this topic discussed in the

> group,

> > I wanted to share this important news with all of you. I hope this

> > helps someone.

> >

> > Homekeeper

> >

>

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In PANDAS (Pediatric Autoimmune Neuropsychiatric Disorders

Associate with Streptococcal infections - qutie a mouthful)

autoimmunity is directed at the heart valves and the basal ganglia.

When the heart valves are attacked, it creates a condition similar to

rhumatic fever. When the basal gangia are attacked, it creates

various psychiatric manifestations.

PANDAS by definition only occurs in pre-pubescent children. I

don't know if this is because it *can't* occur later on (perhaps the

brain isn't fully protected against autoimmunity until puberty), or

whether it's just defined this way. Some thinking is that a lot of

psychiatric conditions have autoimmunity or something like it at

base. Depression in autoimmune thyroid people and perhaps non-

thyroid people seems to involve an immune factor called thryoid-

binding inhibitory immunoglobin (TBII), which may or may not be an

autoantibody or something like it). So it is certainly possible that

the HPA is attacked in subtle ways by the immune system. Or that the

H-P axis is particular affeced by TBII. An article on the link

between anxiet and mood disorders an autoimmunity is here (http://

www.biomedcentral.com/1471-244X/4/25).

An interesting thing is that the psychiatric symptoms of PANDAS

seem to resolve with time - until another strep infection triggers to

autoimmunity. This implies that the brain is capable of regenerating

the basal ganglia with time.

Darts might somehow " re-coordinate " the H-P link of the HPA axis

somehow, at least temporarily. It would be interesting if anythig

else " helps " (tennis, or other things that call for hand-eye, or body-

eye co-ordination). The application of PS to the " third eye " is

interesting - I wonder if that's just " folk lore " and doesn't really

have an effect, or if it somehow gets directly to the pituitary or

pineal gland. I would doubt it as it would first have to get through

the skull :), but there might be neurons which project out that are

directly affected by the PS. I think the connection between the eye

and the hypothalamus that has to do with light-sensing/biorhythm-

entrainment is direct (not through the visual cortex). This might

make sense evolutionarily with " lower " organisms that have light-

entrained rhythms but not much of a developed visual cortex -

considering that the hypothalamus is part of the very old " reptile

brain " IIRC.

Jim

> Yes, VERY interesting! I'm also wondering now if the axis may be

> wounded by autoimmune disorders as well??? -

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I'm wondering how this would work since phosphatidylserine is

recommended for people with HIGH cortisol, to help lower itthe stress

hormones. If you're taking HC to increase cortisol, aren't you

going against what you're trying to achieve by taking PS? maybe Val

or someone here can explain this...?

thanks,

Liz

>

> I have been suffering for nearly two years with Adrenal Exhaustion,

> anxiety and a few panic attacks. I'm on Armour Thyroid and

> bio-identical hormones, too. I have a small goiter with cysts, which

> have barely grown in two years, according to the recent ultrasound.

>

> I'm looking so forward to March when I first see a hopefully, good

> doctor that not only uses Armour Thyroid but does saliva testing!!

> and, I've heard, understands Adrenal Exhaustion.

>

> In the meantime, I went to a licensed nutritionalist (which has a

lot

> of medical school training) and does muscle testing too for what

> supplements your body needs. I believe she is on to something

> interesting that no other doctor mentioned.....

>

> She said it may be my hypothalimus-pituitary axis that is damaged or

> unbalanced and to take phosphitidal serine (PS). I put the cream on

> the third eye (middle of forehead where it gets absorbed and can

even

> avert a possible panic attack. Also, I've been taking two capsules

> with breakfast.

>

> Here's the interesting part: My husband and I just came back from

> watching our 5 month old teething grandson that I had to feed every

> 2-3 hours around the clock. We also watched his three year old

> brother that, though loving, shall we say, is THE MOST defiant,

> trying, manipulative child, ever!!! You can not imagine the physical

> and emotional turmoil we were in for 8 days! Before we left I

thought

> I'd end up in bed the whole time taking care of the baby, come home

> and die. WELL------- as soon as I started watching the kids I went

> into what my husband called, " Mommy Mode. " I went like the Eveready

> Bunny the whole time, mostly full of energy, just doing what had to

be

> done. Before we left I could only function for four or five hours in

> the morning. The rest of the time I was 'couch sitting.' I've been

> home for six days and now I'm starting to tire, but not like before

we

> left.

>

> The day after we came home I went to my nutritionalist and she said

> though I still need my hormones and thyroid balanced and have

Adrenal

> Fatigue, because of when I focus, I'm so much better she thought

part

> of my problem might be my hypothalimus-pituitary axis.

>

> The first time I saw her I told her the only time I felt good

> (emotionally and physically) was when I played darts for a few

minutes

> with my husband. Before I did, I could barely move because I was so

> physically wiped out, not from

> doing anything physical. After a minute or two of playing darts

> (which I'm not particularly fond of) I felt soooooo much better.

This

> is what made her think there MAY be a need for PS. After the

> grandchildren experience, she really believes my

> hypothalimus-pituitary axis is the greater problem. Possibly from a

> past sinus infection or candida got up there.

>

> I'm still taking my PS, orally and topically and taking Lion's Mane,

> Nerve Factors. I'm also now taking Caprilic Acid gelcaps and

Oregamax

> to knock out the candida/fungus. She also wants me to focus on a

> flame a few times a

> day and do to cross-stitch or some other type of needlework. Ha, and

> to keep playing darts.

>

> It is just amazing the world of difference since I went to watch my

> grandchildren. Before I didn't ever think I would heal my AF, since

> it was not improving and so, mentally, I was worsening. Now, I'm so

> much better. Still in need of balancing my other physical problems,

> hopefully, with a knowledgeable doctor next month. But, in the

> meantime, and since I haven't seen this topic discussed in the

group,

> I wanted to share this important news with all of you. I hope this

> helps someone.

>

> Homekeeper

>

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I appreciated the article link. I have indeed read that before, and

will recommend it to a friend who has Parkinson's.

I tried Phosphorylated Serine on my ND's recommendation, but it made

me very tired. So I looked it up, and found out that it lowers

cortisol! Yikes, that was the last thing I needed. However, I did try

taking it at night to help with my 3-5 a.m. wakefulness, and it worked

for that, but I just couldn't get going in the morning when I'd get up!

Phosphatidyl Serine is also used for lowering cortisol. So I don't

know if there's a way to take it where it wouldn't aggravate adrenal

fatigue. I've never heard of it in a cream. Where do you get that?

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Share on other sites

>

> In PANDAS (Pediatric Autoimmune Neuropsychiatric Disorders

> Associate with Streptococcal infections - qutie a mouthful)

> autoimmunity is directed at the heart valves and the basal ganglia.

> When the heart valves are attacked, it creates a condition similar to

> rhumatic fever. When the basal gangia are attacked, it creates

> various psychiatric manifestations.

>

> PANDAS by definition only occurs in pre-pubescent children. I

> don't know if this is because it *can't* occur later on (perhaps the

> brain isn't fully protected against autoimmunity until puberty), or

> whether it's just defined this way. Some thinking is that a lot of

> psychiatric conditions have autoimmunity or something like it at

> base. Depression in autoimmune thyroid people and perhaps non-

> thyroid people seems to involve an immune factor called thryoid-

> binding inhibitory immunoglobin (TBII), which may or may not be an

> autoantibody or something like it). So it is certainly possible that

> the HPA is attacked in subtle ways by the immune system. Or that the

> H-P axis is particular affeced by TBII. An article on the link

> between anxiet and mood disorders an autoimmunity is here (http://

> www.biomedcentral.com/1471-244X/4/25).

>

> An interesting thing is that the psychiatric symptoms of PANDAS

> seem to resolve with time - until another strep infection triggers to

> autoimmunity. This implies that the brain is capable of regenerating

> the basal ganglia with time.

>

> Darts might somehow " re-coordinate " the H-P link of the HPA axis

> somehow, at least temporarily. It would be interesting if anythig

> else " helps " (tennis, or other things that call for hand-eye, or body-

> eye co-ordination). The application of PS to the " third eye " is

> interesting - I wonder if that's just " folk lore " and doesn't really

> have an effect, or if it somehow gets directly to the pituitary or

> pineal gland. I would doubt it as it would first have to get through

> the skull :), but there might be neurons which project out that are

> directly affected by the PS. I think the connection between the eye

> and the hypothalamus that has to do with light-sensing/biorhythm-

> entrainment is direct (not through the visual cortex). This might

> make sense evolutionarily with " lower " organisms that have light-

> entrained rhythms but not much of a developed visual cortex -

> considering that the hypothalamus is part of the very old " reptile

> brain " IIRC.

What is PS?

8)

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> I appreciated the article link. I have indeed read that before, and

> will recommend it to a friend who has Parkinson's.

>

Keep in mind that most if not all PS now is derived from soy sources,

not bovine sources as it used to be (thanks to Mad Cow Disease). The

fatty acids (specifically DHA) attached to it are different, and

there appears to be question as to how much cognitive effect the soy-

PS has vs the bovine-PS. See various articles linked here (http://

scholar.google.com/scholar?client=safari & rls=en & q=phosphatidylserine

+soy & ie=UTF-8 & oe=UTF-8 & um=1 & sa=N & tab=ws). I haven't looked into it

in detail.

Jim

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At this point I'm not yet on HC. Maybe next month after new doc sees

my new saliva test results. I'm to do the diurnal cortisol & other

hormone panels a few weeks before my appointment.

That is a good question since I may need PS for my brain neurons and

yet there is the lowering of HC question??

Homekeeper

> >

> > I have been suffering for nearly two years with Adrenal Exhaustion,

> > anxiety and a few panic attacks. I'm on Armour Thyroid and

> > bio-identical hormones, too. I have a small goiter with cysts, which

> > have barely grown in two years, according to the recent ultrasound.

> >

> > I'm looking so forward to March when I first see a hopefully, good

> > doctor that not only uses Armour Thyroid but does saliva testing!!

> > and, I've heard, understands Adrenal Exhaustion.

> >

> > In the meantime, I went to a licensed nutritionalist (which has a

> lot

> > of medical school training) and does muscle testing too for what

> > supplements your body needs. I believe she is on to something

> > interesting that no other doctor mentioned.....

> >

> > She said it may be my hypothalimus-pituitary axis that is damaged or

> > unbalanced and to take phosphitidal serine (PS). I put the cream on

> > the third eye (middle of forehead where it gets absorbed and can

> even

> > avert a possible panic attack. Also, I've been taking two capsules

> > with breakfast.

> >

> > Here's the interesting part: My husband and I just came back from

> > watching our 5 month old teething grandson that I had to feed every

> > 2-3 hours around the clock. We also watched his three year old

> > brother that, though loving, shall we say, is THE MOST defiant,

> > trying, manipulative child, ever!!! You can not imagine the physical

> > and emotional turmoil we were in for 8 days! Before we left I

> thought

> > I'd end up in bed the whole time taking care of the baby, come home

> > and die. WELL------- as soon as I started watching the kids I went

> > into what my husband called, " Mommy Mode. " I went like the Eveready

> > Bunny the whole time, mostly full of energy, just doing what had to

> be

> > done. Before we left I could only function for four or five hours in

> > the morning. The rest of the time I was 'couch sitting.' I've been

> > home for six days and now I'm starting to tire, but not like before

> we

> > left.

> >

> > The day after we came home I went to my nutritionalist and she said

> > though I still need my hormones and thyroid balanced and have

> Adrenal

> > Fatigue, because of when I focus, I'm so much better she thought

> part

> > of my problem might be my hypothalimus-pituitary axis.

> >

> > The first time I saw her I told her the only time I felt good

> > (emotionally and physically) was when I played darts for a few

> minutes

> > with my husband. Before I did, I could barely move because I was so

> > physically wiped out, not from

> > doing anything physical. After a minute or two of playing darts

> > (which I'm not particularly fond of) I felt soooooo much better.

> This

> > is what made her think there MAY be a need for PS. After the

> > grandchildren experience, she really believes my

> > hypothalimus-pituitary axis is the greater problem. Possibly from a

> > past sinus infection or candida got up there.

> >

> > I'm still taking my PS, orally and topically and taking Lion's Mane,

> > Nerve Factors. I'm also now taking Caprilic Acid gelcaps and

> Oregamax

> > to knock out the candida/fungus. She also wants me to focus on a

> > flame a few times a

> > day and do to cross-stitch or some other type of needlework. Ha, and

> > to keep playing darts.

> >

> > It is just amazing the world of difference since I went to watch my

> > grandchildren. Before I didn't ever think I would heal my AF, since

> > it was not improving and so, mentally, I was worsening. Now, I'm so

> > much better. Still in need of balancing my other physical problems,

> > hopefully, with a knowledgeable doctor next month. But, in the

> > meantime, and since I haven't seen this topic discussed in the

> group,

> > I wanted to share this important news with all of you. I hope this

> > helps someone.

> >

> > Homekeeper

> >

>

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It's called Adrenal Calm and I got it at the health food store. It's

quite expensive yet, seems very important.

Homekeeper

>

> I appreciated the article link. I have indeed read that before, and

> will recommend it to a friend who has Parkinson's.

>

> I tried Phosphorylated Serine on my ND's recommendation, but it made

> me very tired. So I looked it up, and found out that it lowers

> cortisol! Yikes, that was the last thing I needed. However, I did try

> taking it at night to help with my 3-5 a.m. wakefulness, and it worked

> for that, but I just couldn't get going in the morning when I'd get up!

>

> Phosphatidyl Serine is also used for lowering cortisol. So I don't

> know if there's a way to take it where it wouldn't aggravate adrenal

> fatigue. I've never heard of it in a cream. Where do you get that?

>

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Thank you, I'll investigate that.

Homekeeper

> > I appreciated the article link. I have indeed read that before, and

> > will recommend it to a friend who has Parkinson's.

> >

> Keep in mind that most if not all PS now is derived from soy sources,

> not bovine sources as it used to be (thanks to Mad Cow Disease). The

> fatty acids (specifically DHA) attached to it are different, and

> there appears to be question as to how much cognitive effect the soy-

> PS has vs the bovine-PS. See various articles linked here (http://

> scholar.google.com/scholar?client=safari & rls=en & q=phosphatidylserine

> +soy & ie=UTF-8 & oe=UTF-8 & um=1 & sa=N & tab=ws). I haven't looked into it

> in detail.

>

> Jim

>

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> >

> > Phosphatidyl Serine is also used for lowering cortisol. So I don't

> > know if there's a way to take it where it wouldn't aggravate adrenal

> > fatigue. I've never heard of it in a cream. Where do you get that?

> >

>

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, thank you for the very informative link!

In my case, my cortisol is very low, a few months ago it was 2 in the

morning and went down to 0 by noon! I do not awake tired. Actually,

I have energy in the morning for four to five hours then I'm pooped

out, to say the least. Then again, I awake in the middle of the

night, sometimes for an hours, sometimes I'm up for the day. That I

think, is from hormone imbalance, low estrogen and NO progesterone,

according to latest blood tests.

So, this is a dilema, isn't it? With short-term memory loss too, I do

think my nutritionalsit hit the nail on the head with the

hypothalamus-pituitary axis being afftected negatively. I just hope

my doc next month realizes that it's more than very low cortisol.

BIG question: If this is so, what if the doc puts me on HC to bring

up my cortisol levels??? That is where the article was a bit

confusing to me. Would that be damaging to my HP Axis? What else

might help the HP Axis? Would healing my HP Axis bring up my cortisol

levels to normal so I could have a normal life in time???

Homekeeper

I know I had high cortisol for many years just based on my symptoms

and think that helped exhaust the adrenals.

> > >

> > > Phosphatidyl Serine is also used for lowering cortisol. So I don't

> > > know if there's a way to take it where it wouldn't aggravate adrenal

> > > fatigue. I've never heard of it in a cream. Where do you get that?

> > >

> >

>

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Mercury toxicity is a very common cause for HPA axis beng messed up.

It especially likes to lodge up in the hypothalamus.

~Inga

> Yes, VERY interesting! I'm also wondering now if the axis may be

> wounded by autoimmune disorders as well???

> Sheila

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