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RE: Prednisolone not working after 1/8 grain increase

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It's the liquid - Pediapred - for which 1ml = 1mg of pred. You helped

me understand that a dose equivalent to the 5mg of HC that I was

taking at bed-time would be 1.25ml so that's what I started on Sat.

night at around 9PM and slept great, but could not really wake up or

think until after noon the next day.

Sunday night I cut it back to 1ml and took it earlier - like 8:30PM

and slept great again but still had trouble waking up or thinking

straight until the afternoon. And the depression was getting worse.

Monday night I took 1ml at 8PM AND increased my Armour by 1/8 grain

for my morning and bed-time doses that day for a total increase of 1/4

grain. That was a mistake, and I thought that I had paid for it with

messed up sleep and back pain yesterday. I also skipped my bed-time

protein snack and the 200mg of mag/citrate powder that I have been

using some b/c it upsets my stomach.

Last night I went back to everything as it was over the weekend,

except that I held the 1/8 grain Armour increase in the AM and added

..1ml to my pred dose for a total dose of 1.1ml. I still woke up at

4AM, totally whacked out of cortisol and was only able to get back to

sleep after taking 2.5mg - BTW, when we wake up like that should we

take the tiny dose or just go for it with 5mg to be sure?

How much earlier should I move it up? I take my fourth dose of HC at

6:30PM so I would almost be taking them together. Is that safe or

advisable? I guess that this is what you mean by how hard it is to

establish a rhythm with prednisolone.

>

> How much Pred are you taking? I would try moving it up earlier. It is

> supposed to last 12 hours but there can be a 3-4 hour delay befoer

it is

> felt.

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I would take it about 7PM doesn;t matter if wiht HC or not it still

works in it's own time anyway. It may have been the not eating or the

stopping mag that was part of waking too.

--

Artistic Grooming- Hurricane WV

http://www.stopthethyroidmadness.com/

http://health.groups.yahoo.com/group/NaturalThyroidHormonesADRENALS/

http://health.groups.yahoo.com/group/RT3_T3/

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But I ate and took mag last night and woke up exactly the same.

When we wake up, better to take just 2.5mg of HC or take 5mg and then

subtract from normal morning dose right?

>

> I would take it about 7PM doesn;t matter if wiht HC or not it still

> works in it's own time anyway. It may have been the not eating or the

> stopping mag that was part of waking too.

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,

I know you don't want to hear this, but if you feel the Armour increase is

messing things up why not back off on it for a bit. It sounds like the Vit.

D episode stressed your adrenals out too much and now they can't handle the

armour increase to me. I know you want to get the armour to an optimal dose

so you will start feeling better, but if you keep putting too much stress on

your adrenals you will never get there. If you try to go up too quickly, you

will only set yourself back that much farther and take that much longer to

get well. That is why we are supposed to go up slowly with HC and thyroid

stuff. Lord knows I understand wanting to just get everything where it

should be, but maybe if you backed up on the armour for another week or so

and let your adreanals recover from the extra stress it would work then.

Slow and steady. We need to be tortoises not hares!

Rie

A positive attitude may not solve all your problems, but it will annoy

enough people to make it worth the effort. Herm Albright

> I'm wiped out now and back already hurts sitting here at work. I have

> a telephone consultation with my doc today and I'm obviously going to

> ask him, but I haven't heard anyone speak of a doctor who knows how to

> properly dose HC and or prednisolone yet. I've taken the pred between

> 8PM and 9:30PM. When I took it late I had a really hard time getting

> up the next day so I moved it up to 8PM like Val had originally said

> so that I would hopefully be able to get up for work. Increasing the

> Armour has really thrown a monkey wrench in the works, but temps were

> fine yesterday and I need to get the Armour up b/c I'm miserable.

>

>

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10:10 AM

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Well I did exactly as my doc and I discussed. I cut the Armour back

to 2 grains and took the pred liquid at 8PM and took the full dose of

1.25ml that I slept great on over the weekend, but then could not wake

up all morning. I also had my mag drink and a snack, just like over

the weekend. Took my Klono and fell dead asleep at 10:30 and then woke

up at 1:45 with a full bladder, dehydrated, sweating, and stomach

growling and full of air. WTH!?! Apparently there is no going back.

For the hell of it, before I ate and took more HC, I tested my blood

sugar (I had last eaten 4 hours before) and it was 112 so I'm assuming

that I was not hypoglycemic. I ate a piece of cheese, took 2.5mg of

HC and, fell back to sleep pretty quickly afterwards untill 4AM when I

woke up sweating again, and the fell right back to sleep until my

alarm went off at 7AM. I was totally in a fog trying to get ready for

and driving to work but I'm more or less normal now. I took 10mg of

HC at 8AM and another 10mg at noon with lunch which was a little late

b/c I had already started feeling dizzy but that feeling has faded.

I really don't what to think about how to dose the pred and HC

together and I can see why Val isn't too eager to suggest it to

people. Should I take it between 6 and 7PM in the hopes that it will

do its thing overnight, still take my 6:30PM and bed-time doses of HC

so that I don't wake up in the middle of the night needing cortisol,

and then take less HC during the day to make up for it? If it's not

hypoglycemia waking me up in the middle of the night can I still be

low cortisol? Maybe it's too much cortisol but then why does the

2.5mg help me get back to sleep? I have no idea how to do this.

>

> If I move that dose of HC to bed-time that leaves a gap of 3:30 or so

> to 10:30 with no HC. I don't think that I would make it.

>

> I guess that I'm going to do as my doc and Cherie suggested today and

> dial back the Armour to 2 grains (I hate to back out of even the 1/8

> but I over did it and can't seem to get recovered, although, despite

> my sleep problems last night I felt better today than yesterday and

> only had to stress dose once) and leave the pred dose where it is at

> 8PM and go back to 1.25 - I would rather sleep and be a zombie than

> wake up hypogly again.

>

>

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Would have dosed 12.5mg at 8AM, 10mg at 11:30AM, 7.5mg at 3PM, 7.5mg

at 6:30PM and then the liquid at 8PM. Because I woke up and had to

take the 2.5mg at 2:30AM I started with 10mg at 8AM and stayed the

same with everything else except that I was a little late for my noon

dose and felt it when I started getting dizzy. Felt it the same right

before my 3PM dose so I'm really not making it much longer than 3

hours which is consistent with waking up the last three nights after

anywhere from 3-5 hours severely needing HC. I'm assuming that the

only reason that I lasted as long as I did the first two nights is

being that tired, and the Klonopin. I think that I would have slept a

little longer, maybe until 8AM, but probably would have dozed a lot

b/c that's how I usually do if I'm lucky enough to be in bed between 7

and 9AM and still able to sleep. My snooze goes off every 9 minutes

(like most) and I was falling asleep in between which I rarely do so I

probably would have slept more. TMI I guess. That's exactly what I'm

trying to figure - is the pred kicking in early and fading. Taking

more has never gotten me right back to sleep like that before, but it

did last night and helped the night before which leads me to believe

that I need more and that it is tapering out. The first two nights

that I took the pred I took it at 9 and 9:30PM because it was over the

weekend and I was going to bed later - 11:30 and midnight instead of

my usual 10:30 - 11PM. And I slept like a champ even after waking to

go to the bathroom (b/c I always have to at least once anyway). I do

seem to be a fast metabolizer of HC, or I get little use out of what I

take b/c of digestion but I am doing a lot to assist with that by

taking enzymes and eating pretty healthily. I tend to believe that I

should take it later rather than earlier, but I guess that there is

only one way to find out. I took it at 8PM the last two nights and

had about the same result. I'm leaning towards taking it at 9 or 9:30

tonight. What do you think?

Thanks Barb,

>

> What is current HC dosing schedule?

>

> When you woke at 4 a.m. and fell back asleep till alarm went off, if

> alarm hadn't gone off do you think you would've slept much longer?

> Trying to figure out if pred kicks in late, like 4 a.m., or early and

> runs out.

>

> Barb

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Well, chalk one up for Val and you b/c I slept, more or less, after

taking it at 7PM AND dosing 2.5mg of cream before I went to bed. I

had to get up twice to urinate and felt dehydrated when I did so

something is messing up my electrolytes, but I did not have to eat or

take HC or anything else in the middle of the night to get back to

sleep. I woke up at around 6:30AM for the last time and laid there

until my alarm went off at 7AM. I'm still totally wiped out and thick

headed this morning, two hours after I got up, so I think now it might

be safe to cut that 1.25ml back to 1ml like I did before although that

didn't make much of a difference last time. I'm also very depressed

but that might be part of being hypo and/or so narc'ed out... it's

two hours later now (had meetings and work to do so had to wake up

some and I'm less mentally affected and depressed.

I don't understand how the dehydration and middle of the night urgency

is involved in this but something has changed there that must mean

something. I'm getting my aldosterone and renin checked again next

week and maybe I'll learn that that has been part of my problem all

along. I also didn't know to not take salt before my last aldosterone

test so I took it that morning and it probably skewed my result. How

many days do I need to salt-fast before having that test done again -

2? Is it just the salted water that I need to stop or even stay away

from salted foods?

Thanks,

>

> Val said take it early before you did and I'm always wrong about this

> stuff so I took it early - at 7PM this time. I'll let you all know

> how it goes.

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