Re: question on medrol/advantan and HC

[Guest guest]

>

> Medrol is 5 times stronger than HC and lasts longer in the body.

>

> --

> Artistic Grooming- Hurricane WV

>

> http://www.stopthethyroidmadness.com/

> http://health.groups.yahoo.com/group/NaturalThyroidHormonesADRENALS/

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>

Okay, thanks. Actually I'm seeing now that the listing for Advantan

says it contains 1mg (0.1%) methylprednisolone. So if 1x MPD equals 5x

HC I'm *assuming* that would mean the same 1/4 tsp that equals 10mg HC

would equal... 0.5mg MPD? ?

Then to yield a 2-4mg maintenance dose of MPD, I guess it would be 1-2

tsps. per day, which seems like kind of a lot. It seems more intuitive

that it would be 10:1, but it's possible my math or hypo-brain

reasoning is off, and the same 1/4 tsp of HC would equal 1mg of Advantan.

I'm also just seeing this, on a website listing the various steroid

drugs:

" Methylprednisolone is used mainly in the management of acute and

chronic steroid-responsive disorders such as anaphylaxis, bronchial

asthma, rheumatoid arthritis and other connective tissue disorders,

and inflammatory reactions. ***It has even less mineralocorticoid

activity than prednisone/prednisolone***, while having a similar

duration of action, and may be preferred when a mineralocorticoid

effect is particularly undesirable. During long-term therapy an

alternate day regimen should be considered. ***It is not suitable for

replacement therapy in adrenal hypofunctional states.*** "

Presumably because of the lack of mineralcorticoid activity? It seems

like a prednisolone cream would in that case be slightly better than

medrol cream. But HC doesn't have much mineralcorticoid activity

either, does it, and that same website states that HC is normally

given for hypoadrenal states in combination with fludrocortisone. So

then why not just MPD + fludro?

I'm confused!

-Jeff

[Guest guest]

> Okay, thanks. Actually I'm seeing now that the listing for Advantan

> says it contains 1mg (0.1%) methylprednisolone. So if 1x MPD equals 5x

> HC I'm *assuming* that would mean the same 1/4 tsp that equals 10mg HC

> would equal... 0.5mg MPD? ?

>

> Then to yield a 2-4mg maintenance dose of MPD, I guess it would be 1-2

> tsps. per day, which seems like kind of a lot. It seems more intuitive

> that it would be 10:1, but it's possible my math or hypo-brain

> reasoning is off, and the same 1/4 tsp of HC would equal 1mg of

Advantan.

wait - I think my math definitely was off. 1/4 tsp. 1% HC cream = 10mg

HC, so 1/4 tsp. 0.1% MPD cream should equal TWO mg of MPD, which seems

to make more sense.

having a hypo-brain is so much fun. O.o

And I guess since the medrol lasts longer in the body, it would only

take a once a day dosing. Is that what people normally do who take

medrol for adrenal support orally?

-Jeff

[Guest guest]

HC I'm *assuming* that would mean the same 1/4 tsp that equals 10mg HC

would equal... 0.5mg MPD? ?

1/4 tsp would equal 10mg medrol. Unless my math is wrong.

--

Artistic Grooming- Hurricane WV

http://www.stopthethyroidmadness.com/

http://health.groups.yahoo.com/group/NaturalThyroidHormonesADRENALS/

http://www.seewell4less.com/Valspage.htm Medical Alert Bracelets