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Re: SRt3 dosing

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>Rt3 674.2 pmol/L (230.0 - 540.0)

>TSH 0.85 mIU/L (0.27- 4.20)

>fT4 16.8 pmol/L (12.0 - 22.0)

>fT3 3.9 pmol/L (3.9 - 6.7)

>

>Are you able to tell me what my ft3/rt3 ratio is?

pretty rubbish as you have guessed, a bottom of range FT3 and over

range RT3 in itself is a warning sign

3900/674 = 5.78 and we are looking for 20 or better

>

>Am in Australia and can only get srT3 to treat, also my doc has only prescribed

20mcg SRt3 in AM. I started with this three weeks ago and have increased to

20mcg in AM and 20mcg in afternoon. Have not noticed a change in temp/pulse on

this dose.

Were you on anything before the SRT3?

you are going to need to increase over a period of weeks to quite a

bit more, SRT3 is often poorly absorbed and weak seeming in

comparison with normal T3 and with a RT3 that high you will have a LOT

of resistance built up.

Depending on the SR compounding it may last 12 hours, in which case

nominally 12 hours apart might work.

I suspect it may not last that long and you will get slumps so if you

do your next increase by going over to 8 hour intervals you will get a

more even performance and an increase at the same time (think of it as

topping up the tank on your car before it's run out, the overall level

increases)

In terms of dosing with standard release T3 " most people " need 75 to

125 to clear hypo symptoms AFTER resistance clears.

As you have the weaker T3 and pretty severe resistance I could see you

getting up towards 200mcg a day after 8 weeks and still feeling hypo.

It might be worth getting some normal T3, I think people have had

success ordering in Australia from Mexico.

Have a read through the web site if you haven't done so already and

feel free to ask questions

www.thyroid-rt3.com

The trick with the dosing is to keep edging up so it lowers TSH,

lowers your own T4 production, and " starves out " the RT3 by taking

away the T4 it is made from.

Nick

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Thanks for all the information, I will talk to my Doc about straight T3, but am

not hopeful. I was not on anything else before SRt3, had very low ferritin (22)

due to another illness, but have managed to get that up. If I have to remain on

SRt3 how often do you think it is safe to increase and by how much each time,

should I try 20mcg every 8 hours for my next increase?

>

> >Rt3 674.2 pmol/L (230.0 - 540.0)

> >TSH 0.85 mIU/L (0.27- 4.20)

> >fT4 16.8 pmol/L (12.0 - 22.0)

> >fT3 3.9 pmol/L (3.9 - 6.7)

> >

> >Are you able to tell me what my ft3/rt3 ratio is?

>

> pretty rubbish as you have guessed, a bottom of range FT3 and over

> range RT3 in itself is a warning sign

>

> 3900/674 = 5.78 and we are looking for 20 or better

>

> >

> >Am in Australia and can only get srT3 to treat, also my doc has only

prescribed 20mcg SRt3 in AM. I started with this three weeks ago and have

increased to 20mcg in AM and 20mcg in afternoon. Have not noticed a change in

temp/pulse on this dose.

>

> Were you on anything before the SRT3?

>

> you are going to need to increase over a period of weeks to quite a

> bit more, SRT3 is often poorly absorbed and weak seeming in

> comparison with normal T3 and with a RT3 that high you will have a LOT

> of resistance built up.

>

> Depending on the SR compounding it may last 12 hours, in which case

> nominally 12 hours apart might work.

>

> I suspect it may not last that long and you will get slumps so if you

> do your next increase by going over to 8 hour intervals you will get a

> more even performance and an increase at the same time (think of it as

> topping up the tank on your car before it's run out, the overall level

> increases)

>

> In terms of dosing with standard release T3 " most people " need 75 to

> 125 to clear hypo symptoms AFTER resistance clears.

>

> As you have the weaker T3 and pretty severe resistance I could see you

> getting up towards 200mcg a day after 8 weeks and still feeling hypo.

>

> It might be worth getting some normal T3, I think people have had

> success ordering in Australia from Mexico.

>

> Have a read through the web site if you haven't done so already and

> feel free to ask questions

>

> www.thyroid-rt3.com

>

> The trick with the dosing is to keep edging up so it lowers TSH,

> lowers your own T4 production, and " starves out " the RT3 by taking

> away the T4 it is made from.

>

> Nick

>

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> > >

> > > >

> > > >Thanks for all the information, I will talk to my Doc about straight T3,

but am not hopeful. I was not on anything else before SRt3, had very low

ferritin (22) due to another illness, but have managed to get that up. If I have

to remain on SRt3 how often do you think it is safe to increase and by how much

each time, should I try 20mcg every 8 hours for my next increase?

> > >

> > > That seems a reasonable increase going over to 8 hour intervals.

> > >

> > > You need to be more cautious about SR than you do normal as an

> > > overdose stays with you longer so you can't dose to " a bit too much

> > > and then back off a notch " .

> > >

> > > Assuming the 20 of SR is similar to 12.5 or 15 of normal you can add

> > > extra doses 1 at a time for increases.

> > >

> > > If you go over to 3 times a day and then start adding an extra to one

> > > of those doses at a time so you go from

> > >

> > > 20, 20 to

> > >

> > > 20, 20, 20

> > >

> > > and then

> > >

> > > 40, 20, 20

> > >

> > > 40 40 20

> > >

> > > 40, 40, 40

> > >

> > > 60, 40 40

> > >

> > > and increase like that at something like weekly intervals bearing in

> > > mind temperature, pulse etc as per the web site

> > >

> > > Nick

> > >

> > > --

> > >

> > > for more information on RT3 and Thyroid Resistance go to

> > >

> > > www.thyroid-rt3.com

> > >

> >

>

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