Guest guest Posted June 25, 2010 Report Share Posted June 25, 2010 Haven't posted in a while as things have been going along O.K with the SRT3 up until just recently. Just to refresh my situation, I am on SRT3 x 3 times daily, and got up to 15,15,5 my doc did another morning saliva test to check E/P/T and AM Cortisol,DHEAs,Melatonoin, These are the results: Test done 3rd May Cortisol AM 30.5 [6.00-42.00]nmol/L Melatonin AM 1 [ 0.3] pg/ml Progesterone(P4) 188.0 LOW DHEAs 7.0 [2.5 -25.0]nmol/L Testosterone 137.0 [25.0 -190.0]pmol/L Salivary Estrogens, Estradiol E2 >200.0 [37.0 -184]pmol/L V.HIGH Estrone E1 45.0 [9.6 -20.0]pg/ml HIGH Estriol E3 <1.0 [0.0 - 41.0]pg/ml LOW Total Saliva Estrogens 246 E1 % 18.3 E2 % 81.3 E3 % 0.4 E3/[E2+E1] 0.00 [>1.0 Ratio V.LOW P4/E2 Ratio [saliva] 0.9 [4.0- 108.0] LOW Estrogen Dominance is the result as you can see, so the doc prescribed Progesterone 160mg [as natural compounded capsules], and also told me to wean off the Sandrena Gel which was estradiol 0.1%, which I have done. I'm also taking as per docs suggestion Indolplex [DIM] to help with rebalancing the Estrogen. She told me not to raise my T3 dose any further as the Progesterone may have the effect of making it work better, but I think she is missing the point about dosing. I have been holding on the SRT3 dose as above since the 31st May and started the Progesterone on the 7th June and the Indolplex on the 28th May, but now I feel like I'm going backwards,this is just not working, I've been very crabby, emotional, and feel like I want to just explode a lot of the time this past week, basal temp went down at the start of the week to 35.8, but have now started to rise a little, it's almost like PMS with adrenal symptoms thrown in,tight throat ,air hunger etc, but I am supposedly post Meno, and have had Hysto, but something is sure causing it, I thought with taking the Progesterone things would have improved, but I'm thinking that the SRT3 needs to be raised? Pulse is up and down, not high tho 68 to 76 I am doubtful about the Cortisol Test at 30.5 as the AM was 6.8, back in November and I'm certainly not bouncing out of Bed in the Morning. I'm taking Sea Salt on my food [as I can't drink it Yuk!] Vit B's,C,D,E, Zinc, Pot/Mag 250mg, stopped Iron as I have High Ferritin and was concerned at supplementing extra. Also not on HC of any kind as doc thinks I'm only mildly adrenal.?? Also I keep reading that the SRT3 is weaker than the normal T3, but can someone explain how this can be, if you have say 10mcg of one and 10mcg of the other surely that is what they are how can it be weaker, what is the difference? I am also just past the 12 weeks since starting the SRT3 its obvious to me that I'm not going to clear my RT3 on this dose and feel that I am just going back into Hypo state? I am at a loss please can you advise. Thanks so much,Val, Nick, other Mods you do such a wonderful job. Sandy Quote Link to comment Share on other sites More sharing options...
Guest guest Posted June 26, 2010 Report Share Posted June 26, 2010 Testign sex hormones while you are on them should always be done with SERUM labs not salivary as they show false highs in saliva or blood spot., Yoour symptoms sound like a combo of hypo an lwo estrogen. The differncein SRT3 and regular I believe is in the absorbtion. I believe it is a difficult med to compound (judging based in the discrepancieis between EVERY brand I ahve taken) evne the big pharmaceutical companys have problems with potency. The generic is no better. http://health.groups.yahoo.com/group/NaturalThyroidHormonesADRENALS/ http://faqhelp.webs.com/ http://health.groups.yahoo.com/group/RT3_T3/ http://www.thyroid-rt3.com/ http://groups.yahoo.com/group/HypoPets/ http://artisticgrooming.net/ > Haven't posted in a while as things have been going along O.K with the SRT3 up until just recently. > Just to refresh my situation, > I am on SRT3 x 3 times daily, and got up to 15,15,5 my doc did another morning saliva test to check E/P/T and AM Cortisol,DHEAs,Melatonoin, > > These are the results: Test done 3rd May > > Cortisol AM 30.5 [6.00-42.00]nmol/L > Melatonin AM 1 [ 0.3] pg/ml > Progesterone(P4) 188.0 LOW > DHEAs 7.0 [2.5 -25.0]nmol/L > Testosterone 137.0 [25.0 -190.0]pmol/L > Salivary Estrogens, > Estradiol E2>200.0 [37.0 -184]pmol/L V.HIGH > Estrone E1 45.0 [9.6 -20.0]pg/ml HIGH > Estriol E3<1.0 [0.0 - 41.0]pg/ml LOW > > Total Saliva Estrogens 246 > > E1 % 18.3 > E2 % 81.3 > E3 % 0.4 > E3/[E2+E1] 0.00 [>1.0 Ratio V.LOW > P4/E2 Ratio [saliva] 0.9 [4.0- 108.0] LOW > > Estrogen Dominance is the result as you can see, so the doc prescribed > Progesterone 160mg [as natural compounded capsules], and also told me to wean off the Sandrena Gel which was estradiol 0.1%, which I have done. > I'm also taking as per docs suggestion Indolplex [DIM] to help with rebalancing the Estrogen. > She told me not to raise my T3 dose any further as the Progesterone may have the effect of making it work better, but I think she is missing the point about dosing. > > I have been holding on the SRT3 dose as above since the 31st May and started the Progesterone on the 7th June and the Indolplex on the 28th May, but now I feel like I'm going backwards,this is just not working, I've been very crabby, emotional, and feel like I want to just explode a lot of the time this past week, basal temp went down at the start of the week to 35.8, but have now started to rise a little, it's almost like PMS with adrenal symptoms thrown in,tight throat ,air hunger etc, but I am supposedly post Meno, and have had Hysto, but something is sure causing it, I thought with taking the Progesterone things would have improved, but I'm thinking that the SRT3 needs to be raised? Pulse is up and down, not high tho 68 to 76 > > I am doubtful about the Cortisol Test at 30.5 as the AM was 6.8, back in November and I'm certainly not bouncing out of Bed in the Morning. > > I'm taking Sea Salt on my food [as I can't drink it Yuk!] Vit B's,C,D,E, Zinc, Pot/Mag 250mg, stopped Iron as I have High Ferritin and was concerned at supplementing extra. Also not on HC of any kind as doc thinks I'm only mildly adrenal.?? > > Also I keep reading that the SRT3 is weaker than the normal T3, but can someone explain how this can be, if you have say 10mcg of one and 10mcg of the other surely that is what they are how can it be weaker, what is the difference? > > I am also just past the 12 weeks since starting the SRT3 its obvious to me that I'm not going to clear my RT3 on this dose and feel that I am just going back into Hypo state? > I am at a loss please can you advise. > > Thanks so much,Val, Nick, other Mods you do such a wonderful job. > > Sandy > > > > > > > > > > > > > > ------------------------------------ > > We are not medical professionals here, just patients sharing our experiences. Please use this information with the help of a competent doctor. Yahoo! Groups Links > > > > > Quote Link to comment Share on other sites More sharing options...
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