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Questions on first DMSA rounds

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I've done two rounds with DMSA & notice I actually feel better taking it by the

second day. Since my first round went well at 25 mg, I went up to 50mg for the

second one.

#1)My urinary tract has felt slightly irritated. Is that is to be expected?

It's important to know this before starting another round because I did have a

strep-type bladder infection in November. Is it normal for urine to be

concentrated and have a very strong & unusual odor while taking DMSA? Is it

normal to be drinking more water and urinating more often? (I think I'm

drinking more water due to taking pills so often & have to get up in the night.)

I've been keeping my pH on the alkaline side - is that the correct thing to do?

#2)Typically my heart rate is quite low (50's - low 60's) with no known

heart/artery issues and low cholesterols other than the 'good' one, which is

elevated a little. While I've been on DMSA, however, my heart rate has really

sped up. In fact, it was keeping me awake a bit in the night when there

shouldn't be much T3 in my system. I suspect my pulse was holding steady at

around 90 bpm.

Poor thyroid has been my most serious complication, and I split 1 1/2 tablets

of Cytomel (T3) over the day for this, and on 5-6 days a week take 10 mg

Adderall twice per day, which makes thyroid medication considerably more

effective. With Adderall, I can stay awake and alert fairly consistently while

sitting for about 4-5 hours at a time; without it, I'm in and out unless

standing up and physically active. In fact, while sitting, I go from dozing to

very low levels of alertness every 20 minutes or so, and have been this way for

over 10 years. My heart rate slows & then speeds up a few minutes in this

cycle. No tests ever show problems with insulin levels (also tests low &

considered 'good') or hypoglycemia and my diet is very low in sugars & wheat

free. All of my hormones test low without supplemental meds/supplements, except

one-time blood cortisol (saliva cortisol runs low).

In the early months after my amalgams were removed, I had to stop taking T3

because it was building up to extremely high levels in my blood stream, although

I was feeling good & not hyperthyroid during that time. A few months later it

plummeted very low again.

Is it possible that detoxing with DMSA could be bringing on a heightened

reaction to T3? Or cause it to be building up in my blood stream again? If

this type of detox means I could begin weaning off a little Cytomel, it would be

wonderful.

Is there another reason why my heart rate would increase so much while on

DMSA, independent of thyroid?

#3) Since I do feel quite good on DMSA, is it okay to increase the dose more

quickly than the schedule recommends? It's two years since my amalgams were

removed, and I've only tried ALA (and the things groups like the IAOMT

recommend) as a chelator since then, on and off, with poor reactions. We

suspect I have a lot of mercury in deeper tissues & brain/endocrine glands with

lower levels in the bloodstream. I'd like to get going with ALA as soon as

possible, but also want to do this safely. My hope is to take 100 mg DMSA with

25 mg ALA within a few rounds if my body accepts that reasonably well.

My testing has shown arsenic, lead & some cadmium in addition to mercury,

along with all the usual amalgam metals, and my 'total toxic elements' range in

hair testing had the highest score.

If a scheduled conference with Andy would be best, please let me know. I

strongly suspect I'll have to really learn to 'read' signs of excess thyroid

myself and be prepared to adjust my own dosages.

Joanne

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