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Maternal second-cousin: Generalized Joint/Muscle pain, fatigue, trouble getting up, but early bedtime, dysthymia

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Hi,

A mystery:

My second cousin (mother's grandson) has what he describes pain in

his joints, lower back, neck (like a tension headache he describes),

and muscles. It's constant in presence, but not in intensity. He

doesn't drink anything caffeinated, and isn't diabetic. At least not

Type 1 (it would have shown by now), perhaps Type 2 - his grandmother

is Type 2. He says he craves ice-water constantly. But pain is not

generally a symptoms of diabetes, is it? He gets up at around 7 in

the morning, but takes about an hour and a half to get up. Goes to

bed at 9 or 10, is fatigued " all the time " (as he reports it,

although it doesn't really show - maybe to someone looking). He did

go through a period of 1-2 years (before all this started) of major

depression, and was put on " every pychotropic known to man " (totally

irresponsible medicine) - including neuroleptics. I'm not sure if

neuroleptics have been implicated in pain/fatigue syndromes, but he

doesn't have any tics indicative of dyskinesia. He saw a

neurologist, who did a " needle in leg, then straighten leg " test - I

assume perhaps testing nerve conduction? This doc said he had never

seen anyone with as extensive nerve damge at age *21* - he's 25 or 26

now. This was after his " trip through neuro-pharmacopia " .

It's not rhumathoid arthritis (I assume he was checked for

antibodies, although I wouldn't bet on it), says they didn't think it

was FMG (but, like 's daughter, apparently has a high pain

threshold, so may be able to " hide " it). Has never had a thyroid

test (for all the good the normal test would do), or any adrenal tests.

I of course am thinking either thyroid, or adrenals - and I

actually have an extra DTI kit here he could use - if they will let

me change the info on the sheet as to age. Can anyone think of any

other " diagnostic markers " to look for? He doesn't have the puffy

face that is seen with extreme adrenal problems, or hypoT, but then I

don't know quite what to look for. I also don't know if there is a

characteristic " look " for Graves disease, or Cushings - or whether

the symptom pattern fits it. He is not thin, but not overweight

either, which *might* suggest against hypoT (but then, not everyone

gains weight). It might also suggest against Cushings, which I read

involves weight gaine (but perhaps not always).

Any ideas? Strange autoimmunities not tested for (polymyositis

for instance) - or is rhumathoid arthritis NOT tested for by

antibody? As it should - as ALL autoimmune disorders should be

confirmed if we know the antibody (although negative for antibody

doesn't necessarily mean negative for autoimmunity)

Jim

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