Guest guest Posted August 21, 2007 Report Share Posted August 21, 2007 > How exactly is a person who misses a dose and stops better off than a person who > stops and waits a week? > ------------------ I was wondering the same thing. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 21, 2007 Report Share Posted August 21, 2007 > How exactly is a person who misses a dose and stops better off than a person who > stops and waits a week? > ------------------ I was wondering the same thing. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 22, 2007 Report Share Posted August 22, 2007 > > I too periodically sleep through an ALA dose at night - if it's less than an hour since " cut-off " , > say at 4 hrs, I continue dosing. If it's greater than 1 hr late I stop, but still am not sure why > this makes sense. If redistribution is " caused " by chelator dropping below 1/2 concentration > (at 1/2-life of 3 hrs day or 4 hrs night) TK--- 3hr period for ALA not 4hr , why isn't arresting it at say 1/4 of its level - say at 2 > hrs late - and going back up just a good a solution at stopping (the damage is done already, > isn't it)? TK--- no, the greater fluctuation causes more redistribution > > Is the reason for timing doses to minimize the number of times over the course of chelation > - 1 to 3 yrs - we redistribute? TK--- somewhat - and to minimize the redistribution during each round, it helps to minimize redistribution as much as possible which is the whole reason for the frequent dose protocol Even if we don't screw up at all during rounds, when we stop > each round it's unavoidable at least 52 times on a weekly schedule. TK--- correct there will be some redistribution at the end of each round. How is stopping as the > chelator - which is already redistributing as the 3 (or 4 hr at night) line is crossed, leaving us > better off than just going right back up and sustaining doses as best we can the rest of the > round? TK--- then you have essentually stopped twice that round with the fluctuation redistributing more Hg. How exactly is a person who misses a dose and stops better off than a person who > stops and waits a week? TK--- they redistribute less Hg > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 25, 2007 Report Share Posted August 25, 2007 The rule is largely empirical and people who do it this way (stopping if they miss a dose) feel much better than those who just keep going. Andy > I too periodically sleep through an ALA dose at night - if it's less than an hour since " cut-off " , > say at 4 hrs, I continue dosing. If it's greater than 1 hr late I stop, but still am not sure why > this makes sense. If redistribution is " caused " by chelator dropping below 1/2 concentration > (at 1/2-life of 3 hrs day or 4 hrs night), why isn't arresting it at say 1/4 of its level - say at 2 > hrs late - and going back up just a good a solution at stopping (the damage is done already, > isn't it)? > > Is the reason for timing doses to minimize the number of times over the course of chelation > - 1 to 3 yrs - we redistribute? Even if we don't screw up at all during rounds, when we stop > each round it's unavoidable at least 52 times on a weekly schedule. How is stopping as the > chelator - which is already redistributing as the 3 (or 4 hr at night) line is crossed, leaving us > better off than just going right back up and sustaining doses as best we can the rest of the > round? How exactly is a person who misses a dose and stops better off than a person who > stops and waits a week? > Quote Link to comment Share on other sites More sharing options...
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