Re: Re: thyroid antibodies/low TSH/ miscarriages

July 25, 2006

>>I am not sure if there is a correlation between thyroid antibodies and miscarriage, but you might want to look up Syndrome or antiphospholipid antibody syndrome. It is a autoimmune disease that attacks hormone-producing areas of your body. I have had 2 pregnancy losses, and Hashimotos. <<

I will check into those. Here's the web info I found last night. I'd never heard this before..

Thyroid Antibodies and Miscarriage

Article Title: Thyroid antibody titer and avidity in patients with recurrent miscarriageAuthors and Affiliations: Rhoda , Huang Ling, Marjorie A. MacLean, Mooney, Denis Kinnane, McKillop, and J. ; Glasgow Royal Infirmary and Glasgow Dental Hospital, Glasgow; St. University Hospital, Lees, United Kingdom.Journal: Fertility and Sterility, Volume 71, (March 1999) Number 3, pp. 558-561.

Summarized by M. Schroeder, Ph.D.

Past research has indicated that immune and autoimmune issues may play a role in the complex causes of recurrent spontaneous abortion. Studies focusing upon lupus anticoagulant and other types of phospholipid antibodies found a correlation between miscarriage rates and autoimmune function abnormalities. Several studies have now also suggested a connection between repeated miscarriages and thyroid antibodies.

The focus of the current study was the thyroid peroxidase (TPO) antibody. Two antibody evaluation techniques were used: (1) titer, which measures the absolute amount of antibody in the blood and (2) avidity, which refers to the strength with which the antibodies bonded with their antigens.

Participants in the study were fifteen healthy women in their first trimester of pregnancy. All had a history of three or more miscarriages and tested negative for antinuclear and antiphospholipid antibodies. All women tested positive for TPO antibodies but had normal thyroid functioning at the time of the study. TPO antibodies were measured at the time of entry into the study, as well as in the second and third trimesters.

Seven of the fifteen participants miscarried late in the first trimester. The remaining eight carried successfully to term. The results of the study showed that:

Women who subsequently miscarried had significantly higher first-trimester TPO antibody titers than women who carried to term The number of past miscarriages experienced was not correlated to TPO antibody titers in the first trimester of the current pregnancy In women who carried to term, TPO antibody titers declined significantly throughout the remainder of the pregnancy Like TPO titers, TPO antibody avidity in the first trimester was also higher in women who ultimately miscarried In women who carried to term, TPO antibody avidity increased in the second trimester and then declined in the third trimester

Based on these results, the authors concluded that APO antibodies may be an effective marker of miscarriage risk. However, cause and effect cannot be determined. That is, the APO thyroid antibodies may be the cause of elevated miscarriage risk, or they may simply be caused by an underlying condition that is also increasing the risk of miscarriage.

..

July 25, 2006

WOW...there ya go!! We have some VERY helpful people around here!!! ~E:) ~EG Connecticut T-T 26 months ago - 57.98 mcg Synthetic plus 120 mg Armour = 205.98 mcgs...RATIO: 87 % T4 / 13% T3

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July 25, 2006

>>I am not sure if there is a correlation between thyroid antibodies and miscarriage, but you might want to look up Syndrome or antiphospholipid antibody syndrome. It is a autoimmune disease that attacks hormone-producing areas of your body. I have had 2 pregnancy losses, and Hashimotos. Check it out and see if any of the symptoms fit.<<

None of those symptoms fit me. I guess like thyroid though, it could be simply subclinical and not an obvious thing with symptoms.

..

July 25, 2006

For the week or so, I've been craving salt. Just regular from-the-shaker-salt. It's been hot up here, in the 90's and I don't have any fan or a/c ( pay's been a tad short lately ) so the pups and I work up a sweat reading a book or watching a movie. I drink about half a gallon of water a day, sometimes, 3 qts if I get really hot. I've not craved salt before that I can remember and I only add it to things like spuds. Could this mean something is trying to kick start or am I just wishful thinking? ( I try to keep the salt down to a dull roar, I put a 1/4t in a bowl and grab a bunch of baby carrots. I've not finished the amt of salt I use even tho I eat a good size handful of the carrots. ) Spiff Thyroid stimulation can be caused by Iodine, too much or too little although in the US too much is more common. .

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July 25, 2006

Salt cravings can indicate anemia...

____________________________ in *HHH* Jerseyopen proximal rny 9/18/015'9"-31yo297/168I'm not a doc-in real life or otherwise.***HHH=hot, hazy, & humid!!!

July 25, 2006

Dawn is it the salt itself or the iodine in it? I recently started using raw sea salt...

Sue

Hi Spiff,

Just keep an eye on the salt thing and if it doesn't stop or it gets

worse it could be that your adrenal glands are being stressed which

would be the case with so much heat and the thyroid not working right

Dawn

>

> For the week or so, I've been craving salt. Just regular from-the-

shaker-salt. It's been hot up here, in the 90's and I don't have any

fan or a/c ( pay's been a tad short lately ) so the pups and I work

up a sweat reading a book or watching a movie. I drink about half a

gallon of water a day, sometimes, 3 qts if I get really hot. I've

not craved salt before that I can remember and I only add it to

things like spuds. Could this mean something is trying to kick start

or am I just wishful thinking? ( I try to keep the salt down to a

dull roar, I put a 1/4t in a bowl and grab a bunch of baby carrots.

I've not finished the amt of salt I use even tho I eat a good size

handful of the carrots. )

> Spiff

>

> Thyroid stimulation can be caused by Iodine, too much or too

little

> although in the US too much is more common.

>

> .

>

> ---------------------------------

> How low will we go? Check out Yahoo! Messenger's low PC-to-Phone

call rates.

>

July 25, 2006