SchaferAutismReport: Autism Spectrum Disorders, Schizophrenia Genes Tied to Environment

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From: sarnets-bounces@... On Behalf Of Schafer Autism ReportSent: Thursday, February 09, 2012 7:13 PMTo: Schafer Autism ReportSubject: Autism Spectrum Disorders, Schizophrenia Genes Tied to Environment Read this report online Large text, printer versionThursday February 9, 2012p Reader Supported RESEARCHAutism Spectrum Disorders, Schizophrenia Genes Tied to Environment By Janis Esch thirdage.com A representative gene showing how sex can influence levels of methylation across the lifespan. Each dot represents a different brain. (Credit: Barbara Lipska, Ph.D., NIMH Clinical Brain Disorders Branch) Genes linked to schizophrenia and autism spectrum disorders are members of a select club of genes regulated during environmentally sensitive times, U.S. researchers said. Researchers at the National Institute of Health said a regulatory mechanism that turns genes on and off in the brain's executive hub are among the most environmentally responsive. The mechanism, called DNA methylation -- a biochemical process that is important for normal development in higher organisms -- abruptly switches from off to on within the human brain's prefrontal cortex during this pivotal transition from fetal to post-natal life. As methylation increases, gene expression slows down after birth. This mechanism leaves chemical instructions that tell genes what proteins to make -- what kind of tissue to produce or what functions to activate. Although not part of DNA, these instructions are inherited from a child's parents, but they are also influenced by environmental factors, allowing for change throughout the lifespan, the study said. " Developmental brain disorders may be traceable to altered methylation of genes early in life, " lead author Barbara Lipska, a scientist in the NIH's National Institute of Mental Health said in a statement. " For example, genes that code for theFor rest of today's SAR click here:www.sarnet.org/frm/forsar.htm Today's SAR newslist is human compiled and provided through the support of paid subscriptions. - THANK YOU -$35 for 1 year - or free!www.sarnet.org In This Issue: ••••••••••RESEARCHAutism Spectrum Disorders, Schizophrenia Genes Tied to EnvironmentGene Regulator in Brain's Executive Hub Tracked Across LifespanEnhanced Cortisol Response to Stress in Children in AutismStudy Finds Jolt To The Brain Boosts MemoryChelation Therapy Trial Continued Despite Risks RESOURCESThe Three R's To Bullying Prevention for Students with Autism3-D Technology Helps Autistic Kids Learn To ReadEmployment: Autism and DrivingPEOPLEAutistic Boy Wanders From School, Elementary Didn't Notice COMMENTARYNew DSM Is " Dangerous " Say Experts 'Schafer Autism Report' Now an App on iPhone, iPadand Droid! DO SOMETHING ABOUT AUTISM NOW. . . Read, then Forward the Schafer Autism Report.$35 for 1 year - or free!www.sarnet.org Hundreds of Local Autism EventsWeb / EverywhereAlabamaAlaskaArizonaArkansasCaliforniaColoradoConnecticutDelawareDistrict of ColumbiaFloridaGeorgiaHawaiiIdahoWeb / EverywhereIllinoisIndianaIowaKansasKentuckyLouisianaMainelandMassachusettsMichiganMinnesotaMississippiMissouriWeb / EverywhereMontanaNebraskaNevada New HampshireNew JerseyNew MexicoNew YorkNorth CarolinaNorth DakotaOhioOklahomaOregonPennsylvaniaWeb / EverywhereRhode IslandSouth CarolinaSouth DakotaTennesseeTexasUtahVermontVirginiaWashingtonWest VirginiaWisconsinWyomingWeb / EverywhereSend your LETTER Now's the perfect time to order your free Puzzle Piece kits and launch an autism awareness campaign in your community. When we raise the funding necessary, ARI will see that important research is done, including the large-scale, independent study of vaccinated vs. unvaccinated children Click here. SAR Back Issues The Autism CommunitySupports the Schafer Autism Report. . . Read, then Forward the Schafer Autism Report.$35 for 1 year - or free!www.sarnet.org Biomedical Treatments for Autism Spectrum DisordersScientific References and Abstractswww.autismbiomed.com Copyright Notice: The above items are copyright protected. They are for our readers' personal education or research purposes only and provided at their request. Articles may not be further reprinted or used commercially without consent from the copyright holders. To find the copyright holders, follow the referenced website link provided at the beginning of each item. Lenny Schafer editor@... The Schafer Autism Report is a non-profit corporation Vol. 16 No. 5 Unsubscribe here: www.sarnet.org/frm/unsub2.htm

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