Guest guest Posted February 6, 2008 Report Share Posted February 6, 2008 I am taking 1/2 tsp in the am and pm and heavily salting my food all day long. What do you think about the flashlight test...shouldn't it be better now after being on the Florinef for 8 months? KIm > > Are you taking enough salt with it? You could try increasing salt first > but if the symptoms persist I would increase by 1/4 tab. > > -- > Artistic Grooming- Hurricane WV > > http://www.stopthethyroidmadness.com/ > http://health.groups.yahoo.com/group/NaturalThyroidHormonesADRENALS/ > http://health.groups.yahoo.com/group/RT3_T3/ > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 6, 2008 Report Share Posted February 6, 2008 Val, I went over to STTM and started reading through the long Florinef thread Bob started again...came across this: " As mentioned in the " Anatomy " section, aldosterone is manufactured in the zona glomerulosa of the adrenal cortex. Like coritsol, aldosterone follows a diurnal pattern of secretion with its major peak at around 8:00 AM and major low between midnight and 4:00 AM. Also like coritsol, its production and secretion increases and decreases in response to stimulation of the adrenal cortex by ACTH. This means that aldosterone levels generally rise in stressful situations. However, aldosterone is not part of the negative feedback loop controlling its release. Instead, it depends on the negative feedback loop in which coritsol levels trigger ACTH activity. This means that coritsol determines the amount of ACTH which controls production of both coritsol and aldosterone with aldosterone having no say in the matter. The only thing the cells that produce aldosterone can do to regulate production is to alter their sensitivity to ACTH. Therefore, after about 24 hours, the adrenal cells of the zona glomerulosa become less sensitive to the demands of ACTH and stop manufacturing more aldosterone. The amount of circulating aldosterone then begins to decrease, even though the ACTH levels are high and the need for increased amounts of aldosterone may continue. This decreased production continues until the cells of the zona glomerulosa recover their sensitivity to ACTH, but in the meantime the decreased aldosterone leads to many of the symptoms of adrenal fatigue. Aldosterone is the most important mineralocorticoid, but corticosterone and desoxycorticosterone are also included in this category. The effects of aldosterone depletion can be observed in a large number of hypoadrenic persons. Aldosterone depletion may create one or more different symptoms which are specifically related to the diminished mineralocorticoid levels. " From this info, do you think it would help or hurt to try taking an extra dose at bedtime? In the middle of the night is when I have most of the problems (peeing like crazy, extremely dehydrated). > > Yes it should be better if you are getting enough. > > -- > Artistic Grooming- Hurricane WV > > http://www.stopthethyroidmadness.com/ > http://health.groups.yahoo.com/group/NaturalThyroidHormonesADRENALS/ > http://health.groups.yahoo.com/group/RT3_T3/ > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 6, 2008 Report Share Posted February 6, 2008 Val, I went over to STTM and started reading through the long Florinef thread Bob started again...came across this: " As mentioned in the " Anatomy " section, aldosterone is manufactured in the zona glomerulosa of the adrenal cortex. Like coritsol, aldosterone follows a diurnal pattern of secretion with its major peak at around 8:00 AM and major low between midnight and 4:00 AM. Also like coritsol, its production and secretion increases and decreases in response to stimulation of the adrenal cortex by ACTH. This means that aldosterone levels generally rise in stressful situations. However, aldosterone is not part of the negative feedback loop controlling its release. Instead, it depends on the negative feedback loop in which coritsol levels trigger ACTH activity. This means that coritsol determines the amount of ACTH which controls production of both coritsol and aldosterone with aldosterone having no say in the matter. The only thing the cells that produce aldosterone can do to regulate production is to alter their sensitivity to ACTH. Therefore, after about 24 hours, the adrenal cells of the zona glomerulosa become less sensitive to the demands of ACTH and stop manufacturing more aldosterone. The amount of circulating aldosterone then begins to decrease, even though the ACTH levels are high and the need for increased amounts of aldosterone may continue. This decreased production continues until the cells of the zona glomerulosa recover their sensitivity to ACTH, but in the meantime the decreased aldosterone leads to many of the symptoms of adrenal fatigue. Aldosterone is the most important mineralocorticoid, but corticosterone and desoxycorticosterone are also included in this category. The effects of aldosterone depletion can be observed in a large number of hypoadrenic persons. Aldosterone depletion may create one or more different symptoms which are specifically related to the diminished mineralocorticoid levels. " From this info, do you think it would help or hurt to try taking an extra dose at bedtime? In the middle of the night is when I have most of the problems (peeing like crazy, extremely dehydrated). > > Yes it should be better if you are getting enough. > > -- > Artistic Grooming- Hurricane WV > > http://www.stopthethyroidmadness.com/ > http://health.groups.yahoo.com/group/NaturalThyroidHormonesADRENALS/ > http://health.groups.yahoo.com/group/RT3_T3/ > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 6, 2008 Report Share Posted February 6, 2008 Val, I went over to STTM and started reading through the long Florinef thread Bob started again...came across this: " As mentioned in the " Anatomy " section, aldosterone is manufactured in the zona glomerulosa of the adrenal cortex. Like coritsol, aldosterone follows a diurnal pattern of secretion with its major peak at around 8:00 AM and major low between midnight and 4:00 AM. Also like coritsol, its production and secretion increases and decreases in response to stimulation of the adrenal cortex by ACTH. This means that aldosterone levels generally rise in stressful situations. However, aldosterone is not part of the negative feedback loop controlling its release. Instead, it depends on the negative feedback loop in which coritsol levels trigger ACTH activity. This means that coritsol determines the amount of ACTH which controls production of both coritsol and aldosterone with aldosterone having no say in the matter. The only thing the cells that produce aldosterone can do to regulate production is to alter their sensitivity to ACTH. Therefore, after about 24 hours, the adrenal cells of the zona glomerulosa become less sensitive to the demands of ACTH and stop manufacturing more aldosterone. The amount of circulating aldosterone then begins to decrease, even though the ACTH levels are high and the need for increased amounts of aldosterone may continue. This decreased production continues until the cells of the zona glomerulosa recover their sensitivity to ACTH, but in the meantime the decreased aldosterone leads to many of the symptoms of adrenal fatigue. Aldosterone is the most important mineralocorticoid, but corticosterone and desoxycorticosterone are also included in this category. The effects of aldosterone depletion can be observed in a large number of hypoadrenic persons. Aldosterone depletion may create one or more different symptoms which are specifically related to the diminished mineralocorticoid levels. " From this info, do you think it would help or hurt to try taking an extra dose at bedtime? In the middle of the night is when I have most of the problems (peeing like crazy, extremely dehydrated). > > Yes it should be better if you are getting enough. > > -- > Artistic Grooming- Hurricane WV > > http://www.stopthethyroidmadness.com/ > http://health.groups.yahoo.com/group/NaturalThyroidHormonesADRENALS/ > http://health.groups.yahoo.com/group/RT3_T3/ > Quote Link to comment Share on other sites More sharing options...
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