ALA/DMPS dosage and timing questions

August 2, 2007

Brief Hx:

Mid-January 2007, I began chelation with DMPS post amalgam removal

(15 surfaces total)per Andy Cutler protocol. I began with 25 mg. and

over several courses increased to 75 mg. eventually settling at 50

mg. based on symtoms and tolerance. I continued with 14 rounds of

DMPS every 8 hrs., from 4 to 7 days on per round equal or more days

off between. Results have been remarkable, as my system was in

survival mode 1 year ago. Mid-July, I began ALA 25 mg. every 3 hours

round the clock for 3 full days, combined with DMPS 25 mg. every 8

hours. Symptoms flaired again, though manageably so and by round 2 I

have felt better. I plan to do 2 more rounds at 25mg/25mg before

increasing the ALA on round 5. My questions as follows:

- Given my good response and history, would 50 mg ALA be okay for the

next increase?

- Is there an advantage in terms of mercury removal (and less

redistribution) if I continue a round for 5 or even 7 days with equal

time off, vs. 3 on 4 off?

- Once several rounds into an set dosage of ALA is there any

disadvantage to chelating with ALA alone?

- Ultimately, what is the target dosage of ALA?

- Are there any tests I should be checking on at this point that are

mineral or nutrient specific or otherwise?

(The changes in my endocrine system have been nothing short of

remarkable in 7 months time; Adrenals, Thyroid, and Immune.

Cholesterol had gradually climbed over last 8 yrs. to a high of 275.

Post amalgam removal and 6 months of DMPS my last cholesterol had

dropped to 201.

Thanks for the input and support. May all be well.

Tara

August 3, 2007

>

> Brief Hx:

> Mid-January 2007, I began chelation with DMPS post amalgam removal

> (15 surfaces total)per Andy Cutler protocol. I began with 25 mg. and

> over several courses increased to 75 mg. eventually settling at 50

> mg. based on symtoms and tolerance. I continued with 14 rounds of

> DMPS every 8 hrs., from 4 to 7 days on per round equal or more days

> off between. Results have been remarkable, as my system was in

> survival mode 1 year ago. Mid-July, I began ALA 25 mg. every 3 hours

> round the clock for 3 full days, combined with DMPS 25 mg. every 8

> hours. Symptoms flaired again, though manageably so and by round 2 I

> have felt better. I plan to do 2 more rounds at 25mg/25mg before

> increasing the ALA on round 5. My questions as follows:

>

> - Given my good response and history, would 50 mg ALA be okay for the

> next increase?

>

I would stay at the doses that you are at now. Andy has said that

once you find a comfortable dose (when symptoms flare but are

manageable that sounds like a comfortable dose) chelate away for a

couple of months before increasing dose again.

You were ok with 50 mg DMPS every 8 h so I would think that using 50

mg DMPS every 6-8 h or 25 mg DMPS every 3 h would be ok. Dosing the

DMPS at 3 or 6 h intervals makes it easier to keep track of when ALA

is at 3 h intervals.

> - Is there an advantage in terms of mercury removal (and less

> redistribution) if I continue a round for 5 or even 7 days with equal

> time off, vs. 3 on 4 off?

>

Yes. The redistribution occurs at the end of rounds. With longer

rounds you get more chelating days for the one end of round

redistribution event (which is minimal because we are using low doses).

> - Once several rounds into an set dosage of ALA is there any

> disadvantage to chelating with ALA alone?

>

No. Some people find that DMPS (or DMSA) will help with symptom

control and others find chelation with ALA alone quite manageable.

> - Ultimately, what is the target dosage of ALA?

>

I think that the range Andy recommends is 1/8 to 1/2 mg/lb, so 1/2 mg

per pound would be the target dose. He says not to go above 1 mg per lb.

> - Are there any tests I should be checking on at this point that are

> mineral or nutrient specific or otherwise?

You haven't mentioned whether or not you are taking supplements. The

basic supplements that Andy recommends are needed. I would double

check the lists to be sure that what you are taking is adequate.

You also haven't mentioned much about your history. A routine

physical exam once a year is a good idea. Usually the doctor will do

some routine tests with that.

Other than that, tests would depend on symptoms.

> (The changes in my endocrine system have been nothing short of

> remarkable in 7 months time; Adrenals, Thyroid, and Immune.

> Cholesterol had gradually climbed over last 8 yrs. to a high of 275.

> Post amalgam removal and 6 months of DMPS my last cholesterol had

> dropped to 201.

>

Sounds like you are doing a great job. I'm very happy for you.

J

> Thanks for the input and support. May all be well.

>

> Tara

>

September 30, 2007