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Re: Candida and Gluten share a protein

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thank you! I read this in the yeast connection but it's nice to have something

to print and share with the kids ped and gi doc - wow!

eileen

>

> Patty posted this over at GAPS. I thought it was fascinating so I am

reposting!

>

>

>

> http://www.glutenfreeforum.com/index...ic=27679&st=45

> " Now we come to what to me is the most interesting of the recent research

> regarding celiac. It seems fitting that the research again comes from Holland

,

> where celiac disease was first linked to diet. Dr. Nieuwenhuizen, from the

> research group TNO Nutrition and Food Research, published a paper in the June,

> 2003, Lancet. He links celiac disease with Candida albicans.

>

> Dr. Nieuwenhuizen, knowing the actual sequence of proteins which trigger

celiac

> disease from the published work of other scientists, had searched the

databases

> available to him through TNO to see if the same sequence existed in other

> places. It turns out the identical sequence of proteins occur in the cell

walls

> of Candida albicans. [15]

>

> These Candida gluten-like proteins turn out to be the yeast's

> " hypha-specific surface protein " nicknamed Hwp1. This is the yeast's version

of

> Velcro and allows it to attach and hang onto the endomysium in the wall of the

> intestine. It is also targeted by transglutaminase, the enzyme which acts on

the

> gluten protein and serves as a target for immune antibodies. Candida species

> which don't have this Hwp1 protein can't attach themselves to the digestive

> tract. [16]

>

> If Candida can trigger the same chemical and immunological reactions as wheat

> gluten do we can imagine a number of interesting implications. First, in

people

> with celiac disease, symptoms usually get better rapidly when they eliminate

> gluten from their diet. This isn't always the case. Even without gluten some

> people continue to have symptoms. They may have intestinal Candidiasis. The

> Candida in their gut may be acting like gluten and continues triggering

> symptoms.

> Second, an acute Candida infection may trigger the onset of celiac disease.

Even

> if the Candida is treated and eliminated, the person could be left with a

> permanent sensitivity to wheat gluten.

>

> Candida infections occur frequently with antibiotic usage. In people

> genetically susceptible to celiac, extra caution should be exercised when

using

> antibiotics to prevent Candida overgrowth.

> Third, if wheat can cause neurological damage as in gluten ataxia, it is

> reasonable to assume that Candida could also do so by the same process.

Reports

> of Candida infections causing neurological symptoms are not uncommon; now we

> have a possible explanation.

> Fourth, if only a small portion of the people with gluten ataxia have

> gastrointestinal symptoms despite their severe damage elsewhere in their

bodies,

> it is reasonable to assume that Candida could stimulate significant problems

> while producing slight or no digestive symptoms.

>

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