Guest guest Posted February 17, 2008 Report Share Posted February 17, 2008 My mother has been in bed for 10-20 hours now (don't know when she went to sleep last night). This is highly unusual - she'll usually manage to get up abut 8-10 and have her coffee to get the ACTH/ adrenals stared.. We drove back from Arkansas day before yesterday, and she had a plant swap in another town yesterday, so nothing out of the ordinary stress-wise (at least for stage-0 people). My thoughts are either someting related to diabetes - hyperglycemia (although I usually wake up from hyper-induced fatigue eventually), hypoglycemia coupled with a I presume SERVERLY impaired HPA thus not creating a normal waking response. Her breathing seems normal in rate, which I wouldn't expect with either severe hypo or DKA. Low cortisol/thyroid function is a possibility, as is high estrogen binding thyroid. She is post-menopausal, so it would have to be mostly (all?) adrenal estrogen. Autoimmune thyroiditis seems unlikely as it would have to be extraordinarly fast - unless there is such a thing as autoimmunity against the *conversion enzymes*, which would shut the system down as soon as T3 was used up. RT3 dominance could do the same thing, but would have to be quite severe, and quite rapid to shut down enough of the T4->T3 processing. FM I suppose is a possibility (here for completeness), but there is *nothing* I know in the history that would support it, and it seems more hypochondria-by-proxy on my part. CFS seems in the same boat (too fast an onset), but I don't know (does anyone?) what causes CFS, or whether it's similar to FM - although I'm sure Dr. Lowe is finding out, based on whether CFS but not FM diagnoses respond to his T3 protocol. Could statins (Crestor) produce an effect like this? I know that rhabdomyositis can start very quickly, and at any time. I'm currently reading Pletchnor's Pets At Risk, and wonder if a similar endocrine-immune defect (including the skewed Ig titers) could occur in humans? Cortisol insufficiency certainly can, but has anyone looked that the affect of the immune system? Anyway, how that would create extreme fatigue I don't know. Basically, what tests do I tell them to run? Or if this is transient, should we just drive straight up to Linderman in PA? (The natural hormone replacement specialized DAN! nurse in Indy would probably be open to the proper tests as well). I still have my Diagnos-Tech's box, although the paperwork indicates a 29-y.o. male, not a 61-y.o. menopausal female. Should that be run pronto (she is not on cortisol therapy, so that's not a problem..) RT3 can be gotten from DirectLabs, but it wouldn't be the *same* blood sample that DTI analyzed, although it could be drawn consecutively. Worried, Jim Quote Link to comment Share on other sites More sharing options...
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