Human parvovirus & an ERCP question

[Guest guest]

Hi there,

A " colleague " of mine (a mother of a 7-year-old daughter with

atypical psc) found information on human parvovirus causing

autoimmune disease, among other things. More interestingly, this

seemed to be linked with elevated IgG4 levels which both of our

kids have. Ok, I do not know if all psc patients have elevated IgG4

levels (as one of our other docs seemed to think), but it just

occurred to me to ask if anyone has any information if parvovirus has

anything to do with psc-like symptoms which might not turn out to be

psc after all. This is a possibility in the case of the little girl.

Also, my son happened to have parvovirus infection at the age of 2

and his current hep says he has most likely had psc already before

07/2003.

My son's first ERCP on 19 February confirmed psc dx with caliber

changes all over the intrahepatic ducts and intrahepatic stricturing

in the small ducts which was described as " advanced " although no

stricturing was shown in the MRCP last October. His extraheptic ducts

were ok, though, apart from the intrapancreatic part of the common

bile duct, which was great news. The brush cytology result was benign

inflammation class 2. I had not heard of these classes (unless it

meant staging but it did not sound like that). If there are classes

describing the inflammation, does anyone happen to have any info on

that?

Wishing everyone a good weekend,

Taru-Mari, mother of Eemeli (11), PSC 07/2003, Finland

[Guest guest]

Dear Dave,

Thank you very much for the many interesting links although some of the

implications of higher serum IgG4 levels are not so good.

Even if parvovirus had originally triggered the disease I guess there

is no specific treatment that would cure it even if the cause is

discovered?

Thank you once again and best wishes,

Taru-Mari

(mother of Eemeli (11), PSC 07/2003)