Re: New hypothesis - carboxymethylcellulose

[Guest guest]

Does anyone know if this is in Urso? I looked up the DHA that my

husband takes and it says it has " gelatin " in it - according to

Wikipedia, that could very well be carboxymethylcellulose. Ack... tx,

Nina in Philly

> Bacterial overgrowth and inflammation of small intestine after

> carboxymethylcellulose ingestion

[Guest guest]

Hi Nina;

Ursodiol formulations were discussed in one of our newsletters; see

page 1 of:

http://www.pscpartners.org/NewsVol-1-6.pdf

The Axan Pharma product contains as inactive ingredients:

microcrystalline cellulose, povidone, sodium starch glycolate,

magnesium stearate, ethylcellulose, dibutyl sebacate,

carnauba wax, hydroxypropyl methylcellulose, PEG 3350, PEG 8000,

cetyl alcohol, sodium lauryl sulfate, and hydrogen peroxide.

So there are fillers related to carboxymethylcellulose (i.e.

ethylcellulose and hydroxypropyl methylcellulose) in the Axan brand.

But whether these have the same effects as the carboxymethylcellulose

described in the article that I posted is anyone's guess right now. I

was not aware of this propensity of carboxymethylcellulose to promote

bacterial overgrowth in IL10-deficient mice before .... everything I

have read about it concludes that it is safe. But it's probably never

been tested in this mouse model before.

Gelatin is unrelated to carboxymethylcellulose, and (according to

Wikipedia) is a protein produced by partial hydrolysis of collagen

extracted from the bones, connective tissues, organs, and some

intestines of animals such as the domesticated cattle, and horses.

Best regards,

Dave

(father of (23); PSC 07/03; UC 08/03)

>

> Does anyone know if this is in Urso? I looked up the DHA that my

> husband takes and it says it has " gelatin " in it - according to

> Wikipedia, that could very well be carboxymethylcellulose. Ack...

tx,

>

> Nina in Philly

>

> > Bacterial overgrowth and inflammation of small intestine after

> > carboxymethylcellulose ingestion

>

[Guest guest]

Hi Nina;

Ursodiol formulations were discussed in one of our newsletters; see

page 1 of:

http://www.pscpartners.org/NewsVol-1-6.pdf

The Axan Pharma product contains as inactive ingredients:

microcrystalline cellulose, povidone, sodium starch glycolate,

magnesium stearate, ethylcellulose, dibutyl sebacate,

carnauba wax, hydroxypropyl methylcellulose, PEG 3350, PEG 8000,

cetyl alcohol, sodium lauryl sulfate, and hydrogen peroxide.

So there are fillers related to carboxymethylcellulose (i.e.

ethylcellulose and hydroxypropyl methylcellulose) in the Axan brand.

But whether these have the same effects as the carboxymethylcellulose

described in the article that I posted is anyone's guess right now. I

was not aware of this propensity of carboxymethylcellulose to promote

bacterial overgrowth in IL10-deficient mice before .... everything I

have read about it concludes that it is safe. But it's probably never

been tested in this mouse model before.

Gelatin is unrelated to carboxymethylcellulose, and (according to

Wikipedia) is a protein produced by partial hydrolysis of collagen

extracted from the bones, connective tissues, organs, and some

intestines of animals such as the domesticated cattle, and horses.

Best regards,

Dave

(father of (23); PSC 07/03; UC 08/03)

>

> Does anyone know if this is in Urso? I looked up the DHA that my

> husband takes and it says it has " gelatin " in it - according to

> Wikipedia, that could very well be carboxymethylcellulose. Ack...

tx,

>

> Nina in Philly

>

> > Bacterial overgrowth and inflammation of small intestine after

> > carboxymethylcellulose ingestion

>