Re: Re: Fish oils and Th17 cells - follow-up question

[Guest guest]

What dosage of Fish Oil are people taking?

Thanks so much!

Beth~Marco's Mom

Subject: Re: Fish oils and Th17 cells - follow-up questionTo: Date: Wednesday, June 25, 2008, 7:42 AM

My understanding is that most fish oils will be mercury safe because of the way they remove it from the fish; I THINK that as long as the manufacturer follows "GMP" ("good manufacturing practices") they should be removing mercury and other contaminants during the processing. If you check the various brands' websites a lot of them actually advertise how safe they are - i'm thinking GNC and that Nordic Naturals brand specifically. I have a follow-up question for all the scientists out there - what ratio, ideally, should we be looking for in terms of DHA:EPA. I know there was some discussion a while back about getting as high a proportion of DHA to EPA as possible and my husband currently takes something that is really drastically weighted towards DHA (EPA: 90 mg, DHA: 450 mg, Other Omega-3s: 40 mg, Vitamin E: 15 IU). Should I switch him to something with higher levels of EPA? Thanks,Nina in

Philly> Does anyone know if there is fish oil that is Mercury safe?

[Guest guest]

What dosage of Fish Oil are people taking?

Thanks so much!

Beth~Marco's Mom

Subject: Re: Fish oils and Th17 cells - follow-up questionTo: Date: Wednesday, June 25, 2008, 7:42 AM

My understanding is that most fish oils will be mercury safe because of the way they remove it from the fish; I THINK that as long as the manufacturer follows "GMP" ("good manufacturing practices") they should be removing mercury and other contaminants during the processing. If you check the various brands' websites a lot of them actually advertise how safe they are - i'm thinking GNC and that Nordic Naturals brand specifically. I have a follow-up question for all the scientists out there - what ratio, ideally, should we be looking for in terms of DHA:EPA. I know there was some discussion a while back about getting as high a proportion of DHA to EPA as possible and my husband currently takes something that is really drastically weighted towards DHA (EPA: 90 mg, DHA: 450 mg, Other Omega-3s: 40 mg, Vitamin E: 15 IU). Should I switch him to something with higher levels of EPA? Thanks,Nina in

Philly> Does anyone know if there is fish oil that is Mercury safe?

[Guest guest]

I was taking fish oils for a few months, but stopped due to a re-occuring gallstone. I was told that taking anything high in Omega-3 can contribute to the formation of stones. Has anyone else heard of this? I would like to start taking fish oils again, but am very reluctant because of the chance of stones forming.

Thanks,

-Dave, PSC07, BC, Canada

From: nlr_psc <nlr_1 (AT) hotmail (DOT) com>Subject: Re: Fish oils and Th17 cells - follow-up questionTo: @ yahoogroups. comDate: Wednesday, June 25, 2008, 7:42 AM

My understanding is that most fish oils will be mercury safe because of the way they remove it from the fish; I THINK that as long as the manufacturer follows "GMP" ("good manufacturing practices") they should be removing mercury and other contaminants during the processing. If you check the various brands' websites a lot of them actually advertise how safe they are - i'm thinking GNC and that Nordic Naturals brand specifically. I have a follow-up question for all the scientists out there - what ratio, ideally, should we be looking for in terms of DHA:EPA. I know there was some discussion a while back about getting as high a proportion of DHA to EPA as possible and my husband currently takes something that is really drastically weighted towards DHA (EPA: 90 mg, DHA: 450 mg, Other Omega-3s: 40 mg, Vitamin E: 15 IU). Should I switch him to something with higher levels of EPA? Thanks,Nina in

Philly> Does anyone know if there is fish oil that is Mercury safe?

[Guest guest]

I was taking fish oils for a few months, but stopped due to a re-occuring gallstone. I was told that taking anything high in Omega-3 can contribute to the formation of stones. Has anyone else heard of this? I would like to start taking fish oils again, but am very reluctant because of the chance of stones forming.

Thanks,

-Dave, PSC07, BC, Canada

From: nlr_psc <nlr_1 (AT) hotmail (DOT) com>Subject: Re: Fish oils and Th17 cells - follow-up questionTo: @ yahoogroups. comDate: Wednesday, June 25, 2008, 7:42 AM

My understanding is that most fish oils will be mercury safe because of the way they remove it from the fish; I THINK that as long as the manufacturer follows "GMP" ("good manufacturing practices") they should be removing mercury and other contaminants during the processing. If you check the various brands' websites a lot of them actually advertise how safe they are - i'm thinking GNC and that Nordic Naturals brand specifically. I have a follow-up question for all the scientists out there - what ratio, ideally, should we be looking for in terms of DHA:EPA. I know there was some discussion a while back about getting as high a proportion of DHA to EPA as possible and my husband currently takes something that is really drastically weighted towards DHA (EPA: 90 mg, DHA: 450 mg, Other Omega-3s: 40 mg, Vitamin E: 15 IU). Should I switch him to something with higher levels of EPA? Thanks,Nina in

Philly> Does anyone know if there is fish oil that is Mercury safe?

[Guest guest]

I was taking fish oils for a few months, but stopped due to a re-occuring gallstone. I was told that taking anything high in Omega-3 can contribute to the formation of stones. Has anyone else heard of this? I would like to start taking fish oils again, but am very reluctant because of the chance of stones forming.

Thanks,

-Dave, PSC07, BC, Canada

From: nlr_psc <nlr_1 (AT) hotmail (DOT) com>Subject: Re: Fish oils and Th17 cells - follow-up questionTo: @ yahoogroups. comDate: Wednesday, June 25, 2008, 7:42 AM

My understanding is that most fish oils will be mercury safe because of the way they remove it from the fish; I THINK that as long as the manufacturer follows "GMP" ("good manufacturing practices") they should be removing mercury and other contaminants during the processing. If you check the various brands' websites a lot of them actually advertise how safe they are - i'm thinking GNC and that Nordic Naturals brand specifically. I have a follow-up question for all the scientists out there - what ratio, ideally, should we be looking for in terms of DHA:EPA. I know there was some discussion a while back about getting as high a proportion of DHA to EPA as possible and my husband currently takes something that is really drastically weighted towards DHA (EPA: 90 mg, DHA: 450 mg, Other Omega-3s: 40 mg, Vitamin E: 15 IU). Should I switch him to something with higher levels of EPA? Thanks,Nina in

Philly> Does anyone know if there is fish oil that is Mercury safe?

[Guest guest]

I looked around on medline and found this:

http://www.ncbi.nlm.nih.gov/pubmed/2067314

" Fish oil, enriched with polyunsaturated fatty acids of the omega-3-type

accelerates the nucleation time in healthy subjects.

Janowitz P, Swobodnik W, Wechsler JG, Janowitz A, Saal D, Ditschuneit H.

Abteilung Innere Medizin II, Universität Ulm.

The daily administration of fish oil, containing 1.5 g omega-3-fatty

acids causes a significant decrease in nucleation time (12.1 +/-7.3 vs.

2.0 +/- 1.2 days, p less than 0.001), as well as in biliary cholesterol

saturation and biliary cholesterol composition in 13 healthy subjects.

The nucleation time, cholesterol saturation index and biliary lipids

showed no significant differences in 11 cholesterol gallstone patients

after a six-week treatment period with omega-3-fatty acids. Taurocholate

percentage increased significantly in the gallstone group (10.4 +/- 3.9

vs 13.5 +/- 1.7%, p less than 0.05). The levels of the other bile acids

remained unchanged during the treatment period. Therefore, the incidence

of gallstones might be increased after treatment with fish oil,

containing omega-3-fatty acids. "

There were several other studies that suggested the opposite though, so

I'd say the case is far from being made that omega 3s cause gallstones.

It seems to me the studies that address the actual incidence of

gallstones in people who take fish oil would be a better guide than one

that only looks at bile composition.

athan

[Guest guest]

I looked around on medline and found this:

http://www.ncbi.nlm.nih.gov/pubmed/2067314

" Fish oil, enriched with polyunsaturated fatty acids of the omega-3-type

accelerates the nucleation time in healthy subjects.

Janowitz P, Swobodnik W, Wechsler JG, Janowitz A, Saal D, Ditschuneit H.

Abteilung Innere Medizin II, Universität Ulm.

The daily administration of fish oil, containing 1.5 g omega-3-fatty

acids causes a significant decrease in nucleation time (12.1 +/-7.3 vs.

2.0 +/- 1.2 days, p less than 0.001), as well as in biliary cholesterol

saturation and biliary cholesterol composition in 13 healthy subjects.

The nucleation time, cholesterol saturation index and biliary lipids

showed no significant differences in 11 cholesterol gallstone patients

after a six-week treatment period with omega-3-fatty acids. Taurocholate

percentage increased significantly in the gallstone group (10.4 +/- 3.9

vs 13.5 +/- 1.7%, p less than 0.05). The levels of the other bile acids

remained unchanged during the treatment period. Therefore, the incidence

of gallstones might be increased after treatment with fish oil,

containing omega-3-fatty acids. "

There were several other studies that suggested the opposite though, so

I'd say the case is far from being made that omega 3s cause gallstones.

It seems to me the studies that address the actual incidence of

gallstones in people who take fish oil would be a better guide than one

that only looks at bile composition.

athan

[Guest guest]

Thank you for the information. I am glad to hear that reality is actually opposite of what I have been told. I am going to follow up with my GI on the topic to see where the source of information was.

Subject: Re: Fish oils and Th17 cells - follow-up questionTo: Date: Wednesday, June 25, 2008, 11:19 AM

Hi Dave;This is contrary to what I have read, see for e.g.:Gallstones and gallbladder diseasehttp://www.clarian. org/ADAM/ doc/In-DepthRepo rts/10/000010. htm"Diet plays a role in gallstones. The following discussions are some observations on specific dietary factors. Fats. Although fats (particularly saturated fats found in meats, butter, and other animal products) have been associated with gallstone attacks, some studies have found a lower risk for gallstones in people who consume foods containing monounsaturated fats (found in olive and canola oils) or omega-3 fatty acids (found in canola, flaxseed, and fish oil). Fish oil may be of particular benefit in patients with high triglyceride levels by improving the emptying actions of the gallbladder. "But I would be

interested to see if anyone in the group finds any evidence for omega-3's contributing to stone formation. This would be news to me.Best regards,Dave (father of (23); PSC 07/03; UC 08/03)>> I was taking fish oils for a few months, but stopped due to a re-occuring gallstone. I was told that taking anything high in Omega-3 can contribute to the formation of stones. Has anyone else heard of this? I would like to start taking fish oils again, but am very reluctant because of the chance of stones forming.