Guest guest Posted January 16, 2007 Report Share Posted January 16, 2007 > > What is the dose that we should advocate for with his Hep? There is a Medication Dose Calculator at http://health.groups.yahoo.com/group//?yguid=691802 that you can use to calculate 's dose in mg/kg/day. Papers at http://health.groups.yahoo.com/group//files/High%20Dose%20Usro/ define high dose URSO as 25-30mg/kg/day and greater than 20mg/kg/day. Another paper there, " High-dose ursodeoxycholic acid in primary sclerosing cholangitis: a five year multicenter randomised controlled study, " concluded 23mg/kg/day has no effect on PSC progression. There are other reasons to take URSO, and that is why I want to be on it. But the required dosage for optimum effect has not been established. I personally am not convinced that anything over 20mg/kg/day adds much to its effect (or blood concentration). I am on 17mg/kg/day. > discovered that he had severe allergies to milk, beef, chicken and pork. changed his > diet and has shown no signs of UC symptoms ... It must have been quite a challenge for to eliminate all those foods from his diet. Tim R Quote Link to comment Share on other sites More sharing options...
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