Re: Mayo Study: Verbal notification

[Guest guest]

,

I would keep the pills so you can at least star up a lower dose if the LFT numbers start to rise.

Ian (52) PSC 89

I got a call today from my study Coordinator letting me know about the study suspension, as we all have read for the last two weeks. She told me to stop taking USDA, right away and to return back any unused pills. As has mentioned, they will keep monitoring us for a period of a year. We will be getting the official letters, soon.

The reason why there is numerically more poor outcomes in the UDCA group is because there were more transplantation, as was mentioned last week and also more incidence of developing varices, in the UDCA group.

I did learn that i was on the drug itself which i have already suspected, due to the sharp decline in my enzymes since i started on the high dose. They still want us to send back the 3mo diaries, but with only reporting hospital visits and new medication.

I have already cut on the dose and i was hoping to continue either with a moderate or a mild one, but now it is out of the question for us who were in the study. -- Ian Cribb P.Eng.

[Guest guest]

,

I would keep the pills so you can at least start up a lower dose if the LFT numbers start to rise.

Ian (52) PSC 89

[Guest guest]

Thank you, Ian. I was hoping that i will be able to continue and specially if

my LFT start to rise as you have mentioned. Doctor Chapman, you might have

read,  has a better outcome with a lower dose, i think. But the problem now is

that they will be watching us after stop taking the drug. They do want us to

report every test or a procedure done. So i don't know.

 

 

Subject: Re: Mayo Study: Verbal notification

To:

Date: Tuesday, July 1, 2008, 4:46 AM

,

 

I would keep the pills so you can at least start up a lower dose if the LFT

numbers start to rise.

 

Ian (52) PSC 89

 

 

[Guest guest]

Ian Cribb wrote:

>

> I would keep the pills so you can at least *start* up a lower dose if

> the LFT numbers start to rise.

I think in studies where the medication is provided, it's pretty much

standard operating procedure to have you return the extra meds when

you're done. That's the way it worked in the cellcept study I was in..

they even made me return the empty bottles!

athan