Biochemical response to UDCA & long-term prognosis in PBC

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Biochemical response to ursodeoxycholic

acid (UDCA) in patients with primary biliary cirrhosis (PBC) is variable. It has been recently proposed that an alkaline phosphatase (ALP) decline of more than 40% in baseline

value or a normal level after 1 year of UDCA treatment (Barcelona criteria) could serve as a good marker

of long-term prognosis. Our aim was…….

http://www.ncbi.nlm.nih.gov/pubmed/18752324

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