off topic

[Guest guest]

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Does anyone have any research of findings of PSC

and or UC and/or Crohns diagnosed in infants?

what type of research do you want?

Barb in Texas

Biliary atresia

is a rare form of bile duct blockage that occurs in some infants two weeks to

six weeks after birth, a time when the bile ducts have not completed their

development normally.

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Gastroenterol Hepatol. 1999

Jun;14(6):588-93.

Primary sclerosing cholangitis

in children.

EA.

Division of Gastroenterology and Nutrition, Hospital for Sick

Children and University of Toronto, Ontario,

Canada.

Primary sclerosing cholangitis

(PSC), a chronic inflammatory process affecting the extrahepatic and/or medium

to large bile ducts, is not rare in children. It has

features suggesting an autoimmune pathogenesis, although the mechanism of

tissue damage remains unknown. The clinical

presentation of childhood primary sclerosing cholangitis is highly variable and frequently without obvious

features of cholestasis. Clinical

similarity to autoimmune hepatitis is common. Association

with chronic colitis is less common than in adults. Cholangiography is essential for the diagnosis and

examination of the medium to large intrahepatic ducts is mandatory, as 40% of

children lack extrahepatic duct involvement. Histological

findings may help to distinguish childhood PSC from autoimmune hepatitis. In children, sclerosing cholangitis may also develop secondary to other disease

processes, notably Langerhans histiocytosis,

congenital immunodeficiencies and cystic fibrosis. Neonatal sclerosing cholangitis is chronic inflammatory disease of bile ducts

which presents initially with neonatal cholestasis;

its pathogenesis remains uncertain and may not be the same as for primary sclerosing cholangitis. Effective treatment modalities for childhood PSC remain

undetermined. Liver transplantation is required for

children who progress to biliary cirrhosis and hepatic decompensation.

[Guest guest]

I thought you brilliant people could answer this question for me. How often are

the standard test for Lyme disease WRONG? (false negatives)