What's new for vulvodynia in PudMed - (article)

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Here you go, .... Hugs, Chelle 1: J Reprod Med. 2007 Oct;52(10):912-6. Links Improvement in vulvar vestibulitis with

montelukast. Kamdar N, Fisher L, MacNeill C. Department of Obstetrics and Gynecology, Pennsylvania State University College of Medicine, Hershey, PA 17033, USA. OBJECTIVE: To determine if montelukast treatment improves symptoms in patients with vulvar vestibulitis. STUDY DESIGN: We administered montelukast to a series of patients with vestibulitis seen at the Pennsylvania State University Vulvodynia Clinic over a period of 2.5 years. We reviewed outcomes using a scoring scheme to quantify signs and symptoms, before and after treatment, in 29 montelukast-treated subjects and 18 subjects in a comparison group treated with standard therapies. RESULTS: Subjects treated with montelukast showed an average of 52% in improvement in symptoms as compared to a 15% improvement in the controls (p < 0.0001). CONCLUSION: Montelukast is a viable treatment option for women with vulvar vestibulitis. This

finding implies that leukotrienes have a role in the pathophysiology of vulvar vestibulitis. PMID: 17977165 [PubMed - in process]