Andy: Please explain why to stop round when late

[Guest guest]

I too periodically sleep through an ALA dose at night - if it's less than an

hour since " cut-off " ,

say at 4 hrs, I continue dosing. If it's greater than 1 hr late I stop, but

still am not sure why

this makes sense. If redistribution is " caused " by chelator dropping below 1/2

concentration

(at 1/2-life of 3 hrs day or 4 hrs night), why isn't arresting it at say 1/4 of

its level - say at 2

hrs late - and going back up just a good a solution at stopping (the damage is

done already,

isn't it)?

Is the reason for timing doses to minimize the number of times over the course

of chelation

- 1 to 3 yrs - we redistribute? Even if we don't screw up at all during rounds,

when we stop

each round it's unavoidable at least 52 times on a weekly schedule. How is

stopping as the

chelator - which is already redistributing as the 3 (or 4 hr at night) line is

crossed, leaving us

better off than just going right back up and sustaining doses as best we can the

rest of the

round? How exactly is a person who misses a dose and stops better off than a

person who

stops and waits a week?