Changing DMPS timing every 8hrs, 6 hrs, varies at night?

May 8, 2007

I've been trying to do DMPS every 6 hours because on occasion I have

forgotten to give my child at the 8 hour mark and this is my safety net

- so if we find it more convenient, say to work around a trip to the

pool or bathtime timing at night (which varies) we can move the dosing

time to more than 6 hrs but less than 8. Also, since my child is

tolerating the 8hr timing I figure I can get in an extra dose a day and

perhaps speed her chelation. If it's night and it's 5 hours or more

that my child has been sleeping since her evening dose, and she sleeps

>8hrs usually - usually 9 or sometimes 10hrs - I give her her dose

early so I won't oversleep and miss the 8hr mark, but usually I hit

betweenm 6 and 8 hours which I figure is OK since I hear others using

the 6hr schedule and Andy has said earlier is ALWAYS OK but later isn't.

I read a recent post by TK saying you should stay on chosen timing

during night as you have during the day - has anyone been dosing with a

somewhat variable schedule (might give one dose " early " during day and

one dose early during night - the rest of daily doses are on schedule),

and what were the real (not theoretical) results?

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May 8, 2007

>

> I've been trying to do DMPS every 6 hours because on occasion I

have

> forgotten to give my child at the 8 hour mark and this is my safety

net

> - so if we find it more convenient, say to work around a trip to

the

> pool or bathtime timing at night (which varies) we can move the

dosing

> time to more than 6 hrs but less than 8.

TK--- consistency is the key to preventing redistribution.

Also, since my child is

> tolerating the 8hr timing I figure I can get in an extra dose a day

and

> perhaps speed her chelation.

TK--- trying to speed chelation is often what causes problems for

people, be careful. Doing 6 hr dosing is fine if that is preferable

and works for her. Trying to get an extra dose in per day is not a

good reason to mess with timing as it will not increase chelation to

any degree.

If it's night and it's 5 hours or more

> that my child has been sleeping since her evening dose, and she

sleeps

> >8hrs usually - usually 9 or sometimes 10hrs - I give her her dose

> early so I won't oversleep and miss the 8hr mark

TK--- giving a dose early is fine but then you need to adjust your 6

or 8 hr schedule to the early dose if it is off by a lot.

, but usually I hit

> betweenm 6 and 8 hours

TK--- two hours is too far off to give a dose if it is late.

which I figure is OK since I hear others using

> the 6hr schedule and Andy has said earlier is ALWAYS OK but later

isn't.

TK--- right you can give a dose early but then you need to adjust

your schedule to that dose if it is two hours early.

>

> I read a recent post by TK saying you should stay on chosen timing

> during night as you have during the day

TK--- this is for a perticular person I was posting to and we were

refering to 3hr and 6 hr dosing. please do not take individual posts

out of context in reference to the protocol, this is how people get

confused and make mistakes. Stick with 3, 6 or 8 hr dosing for dmps,

do not go back and forth with a two hour difference.

- has anyone been dosing with a

> somewhat variable schedule (might give one dose " early " during day

and

> one dose early during night - the rest of daily doses are on

schedule),

> and what were the real (not theoretical) results?

TK--- IMO This is a bad idea and will eventually get you in trouble

trying to keep on schedule and I strongly suggest people do not do

this especially with a child. Dosing Consistency [timing] is key to

keeping blood levels of chelator consistent and preventing

redistribution. When you start experimenting with back and forth

timing of any degree you are experimenting and it is not part of the

protocol.

If you want to experiment on yourself where you can tell what is

happening that is your perogative but for the forum we stick with the

protocol so we do not confuse people and then they make mistakes.

May 8, 2007

>

> I've been trying to do DMPS every 6 hours because on occasion I

have

> forgotten to give my child at the 8 hour mark and this is my safety

net

> - so if we find it more convenient, say to work around a trip to

the

> pool or bathtime timing at night (which varies) we can move the

dosing

> time to more than 6 hrs but less than 8.

TK--- consistency is the key to preventing redistribution.

Also, since my child is

> tolerating the 8hr timing I figure I can get in an extra dose a day

and

> perhaps speed her chelation.

TK--- trying to speed chelation is often what causes problems for

people, be careful. Doing 6 hr dosing is fine if that is preferable

and works for her. Trying to get an extra dose in per day is not a

good reason to mess with timing as it will not increase chelation to

any degree.

If it's night and it's 5 hours or more

> that my child has been sleeping since her evening dose, and she

sleeps

> >8hrs usually - usually 9 or sometimes 10hrs - I give her her dose

> early so I won't oversleep and miss the 8hr mark

TK--- giving a dose early is fine but then you need to adjust your 6

or 8 hr schedule to the early dose if it is off by a lot.

, but usually I hit

> betweenm 6 and 8 hours

TK--- two hours is too far off to give a dose if it is late.

which I figure is OK since I hear others using

> the 6hr schedule and Andy has said earlier is ALWAYS OK but later

isn't.

TK--- right you can give a dose early but then you need to adjust

your schedule to that dose if it is two hours early.

>

> I read a recent post by TK saying you should stay on chosen timing

> during night as you have during the day

TK--- this is for a perticular person I was posting to and we were

refering to 3hr and 6 hr dosing. please do not take individual posts

out of context in reference to the protocol, this is how people get

confused and make mistakes. Stick with 3, 6 or 8 hr dosing for dmps,

do not go back and forth with a two hour difference.

- has anyone been dosing with a

> somewhat variable schedule (might give one dose " early " during day

and

> one dose early during night - the rest of daily doses are on

schedule),

> and what were the real (not theoretical) results?

TK--- IMO This is a bad idea and will eventually get you in trouble

trying to keep on schedule and I strongly suggest people do not do

this especially with a child. Dosing Consistency [timing] is key to

keeping blood levels of chelator consistent and preventing

redistribution. When you start experimenting with back and forth

timing of any degree you are experimenting and it is not part of the

protocol.

If you want to experiment on yourself where you can tell what is

happening that is your perogative but for the forum we stick with the

protocol so we do not confuse people and then they make mistakes.

May 8, 2007

> has anyone been dosing with a

> somewhat variable schedule (might give one dose " early " during day and

> one dose early during night - the rest of daily doses are on schedule),

> and what were the real (not theoretical) results?

>

I do something similar to you -- I generally dose every 2.5 hours

during the day, with one 4 hr interval at night, but it's not rigid

because I work around playdate schedules, etc. I might have a day with

two 3 hr intervals mixed in with the 2.5 intervals, or none at all, or

whatever.

For both my 8 yo son and myself, there haven't been any problems doing

it this way. We're both recovering if that's what you mean by real not

theoretical results?

Nell

May 8, 2007

> has anyone been dosing with a

> somewhat variable schedule (might give one dose " early " during day and

> one dose early during night - the rest of daily doses are on schedule),

> and what were the real (not theoretical) results?

>

I do something similar to you -- I generally dose every 2.5 hours

during the day, with one 4 hr interval at night, but it's not rigid

because I work around playdate schedules, etc. I might have a day with

two 3 hr intervals mixed in with the 2.5 intervals, or none at all, or

whatever.

For both my 8 yo son and myself, there haven't been any problems doing

it this way. We're both recovering if that's what you mean by real not

theoretical results?

Nell

May 8, 2007

>

> > has anyone been dosing with a

> > somewhat variable schedule (might give one dose " early " during

day and

> > one dose early during night - the rest of daily doses are on

schedule),

> > and what were the real (not theoretical) results?

> >

>

> I do something similar to you -- I generally dose every 2.5 hours

> during the day, with one 4 hr interval at night, but it's not rigid

> because I work around playdate schedules, etc. I might have a day

with

> two 3 hr intervals mixed in with the 2.5 intervals, or none at all,

or

> whatever.

TK--- Just for clarification - your 1/2 hour to 1hr is ok for some

people with all three chelators but two hour differences [6hr to 8hr

as barbs' post and the subject title indicate] for any including dmps

are not.

>

> For both my 8 yo son and myself, there haven't been any problems

doing

> it this way. We're both recovering if that's what you mean by real

not

> theoretical results?

>

> Nell

>

May 8, 2007

>

> > has anyone been dosing with a

> > somewhat variable schedule (might give one dose " early " during

day and

> > one dose early during night - the rest of daily doses are on

schedule),

> > and what were the real (not theoretical) results?

> >

>

> I do something similar to you -- I generally dose every 2.5 hours

> during the day, with one 4 hr interval at night, but it's not rigid

> because I work around playdate schedules, etc. I might have a day

with

> two 3 hr intervals mixed in with the 2.5 intervals, or none at all,

or

> whatever.

TK--- Just for clarification - your 1/2 hour to 1hr is ok for some

people with all three chelators but two hour differences [6hr to 8hr

as barbs' post and the subject title indicate] for any including dmps

are not.

>

> For both my 8 yo son and myself, there haven't been any problems

doing

> it this way. We're both recovering if that's what you mean by real

not

> theoretical results?

>

> Nell

>

May 8, 2007

>

> > has anyone been dosing with a

> > somewhat variable schedule (might give one dose " early " during

day and

> > one dose early during night - the rest of daily doses are on

schedule),

> > and what were the real (not theoretical) results?

> >

>

> I do something similar to you -- I generally dose every 2.5 hours

> during the day, with one 4 hr interval at night, but it's not rigid

> because I work around playdate schedules, etc. I might have a day

with

> two 3 hr intervals mixed in with the 2.5 intervals, or none at all,

or

> whatever.

TK--- Just for clarification - your 1/2 hour to 1hr is ok for some

people with all three chelators but two hour differences [6hr to 8hr

as barbs' post and the subject title indicate] for any including dmps

are not.

>

> For both my 8 yo son and myself, there haven't been any problems

doing

> it this way. We're both recovering if that's what you mean by real

not

> theoretical results?

>

> Nell

>

May 8, 2007

-----

barb43230@ wrote:

>

> > has anyone been dosing with a

> > somewhat variable schedule (might give one dose " early " during

day and

> > one dose early during night - the rest of daily doses are on

schedule),

> > and what were the real (not theoretical) results?

====> I asked Andy about this specifically, whether there were any rules about

how often or infrequently you could dose the chelators and he told me that the

ONLY rule was that the chelator had to be given with regard to half life or

sooner, even every 10 minutes is fine just not the point past the half life. We

had always dosed her dmsa/ala anywhere from 1 hour to 3 hours during the day to

allow her to participate in ballet classes or social gatherings and this has

worked out fine. I will try and find Andy's post concerning this and forward it

here but the ONLY rule is that the chelator must be dosed no longer than it's

half life.

> >

>

> I do something similar to you -- I generally dose every 2.5 hours

> during the day, with one 4 hr interval at night, but it's not rigid

> because I work around playdate schedules, etc. I might have a day

with

> two 3 hr intervals mixed in with the 2.5 intervals, or none at all,

or

> whatever.

TK--- Just for clarification - your 1/2 hour to 1hr is ok for some

people with all three chelators but two hour differences [6hr to 8hr

as barbs' post and the subject title indicate] for any including dmps

are not.

>

> For both my 8 yo son and myself, there haven't been any problems

doing

> it this way. We're both recovering if that's what you mean by real

not

> theoretical results?

>

> Nell

>

May 8, 2007