Re: Interesting Article on Molecules that cure liver cirrhosis

[Guest guest]

Hi Sam;

Thanks for posting the news article on " Molecules reverse rats' liver

cirrhosis " . This is pretty exciting, and is a very clever use of

vitamin A to target the collagen-producing stellate cells in the

liver. I hope it can be developed into a human therapy soon! For

those interested in the original abstract in PubMed, it is:

Sato Y, Murase K, Kato J, Kobune M, Sato T, Kawano Y, Takimoto R,

Takada K, Miyanishi K, Matsunaga T, Takayama T, Niitsu Y (2008)

Resolution of liver cirrhosis using vitamin A-coupled liposomes to

deliver siRNA against a collagen-specific chaperone. Nat. Biotechnol.

Mar 30 [Epub ahead of print].

http://www.ncbi.nlm.nih.gov/pubmed/18376398

Please contact me privately if you'd like to see the full text.

Best regards,

Dave

(father of (22); PSC 07/03; UC 08/03)

> Molecules reverse rats' liver cirrhosis

> Tuesday, 1 April, 2008