Re: Probiotic administration in patients with ileal pouch-anal anastomosis for UC

[Guest guest]

Too late for us, wish I could have gotten my son to take it.He was on another probiotic, but still got the pouchitis.This is good to share for those who might be having to go this route.LeeThe probiotic VSL#3 prevents pouchitis if started within a week of ileostomy closure and maintains remission following antibacterial treatment in patients with refractory or recurrent pouchitis. Conclusions: We conclude that VSL#3 administration in patients with IPAA modulates the PDAI and expands the number of mucosal regulatory T cells………..

[Guest guest]

-----Original

Message-----

Too late for us,

It’s not too late…..as

it says – “and maintains remission following antibacterial treatment in

patients with refractory or recurrent pouchitis.”

Barb in Texas - Together in the Fight, Whatever it Takes!

Son Ken (33) UC 91 - PSC 99 - Tx 6/21 & 6/30/07 @ Baylor in Dallas

[Guest guest]

Thanks Barb !TIme to mention it to him that he should consider trying it. He takes a probiotic called Flora Q that he is used to taking and did not want to  take the powder VSL #3. But if the pouchitis gets too much...... this is good to know.Lee-----Original Message-----Too late for us, It’s not too late…..as it says – “and maintains remission following antibacterial treatment in patients with refractory or recurrent pouchitis.”  Barb in Texas - Together in the Fight, Whatever it Takes!Son Ken (33) UC 91 - PSC 99 - Tx 6/21 &  6/30/07 @ Baylor in Dallas 

[Guest guest]

Thanks Barb !TIme to mention it to him that he should consider trying it. He takes a probiotic called Flora Q that he is used to taking and did not want to  take the powder VSL #3. But if the pouchitis gets too much...... this is good to know.Lee-----Original Message-----Too late for us, It’s not too late…..as it says – “and maintains remission following antibacterial treatment in patients with refractory or recurrent pouchitis.”  Barb in Texas - Together in the Fight, Whatever it Takes!Son Ken (33) UC 91 - PSC 99 - Tx 6/21 &  6/30/07 @ Baylor in Dallas 

[Guest guest]

Barb,I wasn't able to open the link (I got a cookie error?). Where was this published? I just had a scope of my pouch yesterday, and I seem to have a pretty bad case of pouchitis. My hepatologist doesn't want me on VSL#3 because he's worried about liver toxicity. But if he sees the article, maybe he'll change his mind. Pouchitis really sucks. And the VSL#3 may be better than antibiotics. Sorry about the bold, but my cat is using the computer at the same time I am, with unintended consequences. LOL.Marie

To: From: barbhenshaw@...Date: Thu, 10 Apr 2008 12:48:00 -0500Subject: Probiotic administration in patients with ileal pouch-anal anastomosis for UC

The probiotic VSL#3 prevents

pouchitis if started within a week of ileostomy closure and maintains remission following

antibacterial treatment in patients with refractory or recurrent pouchitis.

Conclusions: We

conclude that VSL#3 administration in patients with IPAA modulates the PDAI and

expands the number of mucosal regulatory T cells………..

http://www3.interscience.wiley.com/cgi-bin/abstract/117905168/ABSTRACT?CRETRY=1 & SRETRY=0

Barb in Texas - Together in the Fight, Whatever it Takes!

Son Ken (33) UC 91 - PSC 99 - Tx 6/21 & 6/30/07 @ Baylor in Dallas

Going green? See the top 12 foods to eat organic.

[Guest guest]

I have not heard of liver toxicity and VSL#3. Is that an issue? Is there a document about that?

arman_shirin@...

Probiotic administration in patients with ileal pouch-anal anastomosis for UC

The probiotic VSL#3 prevents pouchitis if started within a week of ileostomy closure and maintains remission following antibacterial treatment in patients with refractory or recurrent pouchitis.

Conclusions: We conclude that VSL#3 administration in patients with IPAA modulates the PDAI and expands the number of mucosal regulatory T cells………..

http://www3. interscience. wiley.com/ cgi-bin/abstract /117905168/ ABSTRACT? CRETRY=1 & SRETRY=0

Barb in Texas - Together in the Fight, Whatever it Takes!Son Ken (33) UC 91 - PSC 99 - Tx 6/21 & 6/30/07 @ Baylor in Dallas

Going green? See the top 12 foods to eat organic. __________________________________________________

[Guest guest]

I doubt there's an article about VSL#3 & liver toxicity. But there probably hasn't been a study showing that there ISN'T liver toxicity with VSL#3. I'm not sure what studies have been done with VSL#3. Is it listed in the Physician's Desk Reference? If so, is liver toxicity a possible side effect? My hepatologist is particularly leery of supplements, since there aren't good studies of them, and it's thus next to impossible to know of side effects. I think he sees several cases a year of patients with liver toxicity from supplements. I think in Feb. 2007 UCLA did 2 liver transplants on patients whose livers shut down from tylenol use. I do take a probiotic, but it's not as potent as VSL#3. I'm willing to take VSL#3, but it would be nice to see more scientific information about it that I can show my hepatologist.Marie

To: From: arman_shirin@...Date: Thu, 10 Apr 2008 12:17:31 -0700Subject: Re: Probiotic administration in patients with ileal pouch-anal anastomosis for UC

I have not heard of liver toxicity and VSL#3. Is that an issue? Is there a document about that?

arman_shirin (AT) yahoo (DOT) com

Probiotic administration in patients with ileal pouch-anal anastomosis for UC

The probiotic VSL#3 prevents pouchitis if started within a week of ileostomy closure and maintains remission following antibacterial treatment in patients with refractory or recurrent pouchitis.

Conclusions: We conclude that VSL#3 administration in patients with IPAA modulates the PDAI and expands the number of mucosal regulatory T cells………..

http://www3. interscience. wiley.com/ cgi-bin/abstract /117905168/ ABSTRACT? CRETRY=1 & SRETRY=0

Barb in Texas - Together in the Fight, Whatever it Takes!Son Ken (33) UC 91 - PSC 99 - Tx 6/21 & 6/30/07 @ Baylor in Dallas

Going green? See the top 12 foods to eat organic. __________________________________________________

[Guest guest]

I doubt there's an article about VSL#3 & liver toxicity. But there probably hasn't been a study showing that there ISN'T liver toxicity with VSL#3. I'm not sure what studies have been done with VSL#3. Is it listed in the Physician's Desk Reference? If so, is liver toxicity a possible side effect? My hepatologist is particularly leery of supplements, since there aren't good studies of them, and it's thus next to impossible to know of side effects. I think he sees several cases a year of patients with liver toxicity from supplements. I think in Feb. 2007 UCLA did 2 liver transplants on patients whose livers shut down from tylenol use. I do take a probiotic, but it's not as potent as VSL#3. I'm willing to take VSL#3, but it would be nice to see more scientific information about it that I can show my hepatologist.Marie

To: From: arman_shirin@...Date: Thu, 10 Apr 2008 12:17:31 -0700Subject: Re: Probiotic administration in patients with ileal pouch-anal anastomosis for UC

I have not heard of liver toxicity and VSL#3. Is that an issue? Is there a document about that?

arman_shirin (AT) yahoo (DOT) com

Probiotic administration in patients with ileal pouch-anal anastomosis for UC

The probiotic VSL#3 prevents pouchitis if started within a week of ileostomy closure and maintains remission following antibacterial treatment in patients with refractory or recurrent pouchitis.

Conclusions: We conclude that VSL#3 administration in patients with IPAA modulates the PDAI and expands the number of mucosal regulatory T cells………..

http://www3. interscience. wiley.com/ cgi-bin/abstract /117905168/ ABSTRACT? CRETRY=1 & SRETRY=0

Barb in Texas - Together in the Fight, Whatever it Takes!Son Ken (33) UC 91 - PSC 99 - Tx 6/21 & 6/30/07 @ Baylor in Dallas

Going green? See the top 12 foods to eat organic. __________________________________________________

[Guest guest]

I doubt there's an article about VSL#3 & liver toxicity. But there probably hasn't been a study showing that there ISN'T liver toxicity with VSL#3. I'm not sure what studies have been done with VSL#3. Is it listed in the Physician's Desk Reference? If so, is liver toxicity a possible side effect? My hepatologist is particularly leery of supplements, since there aren't good studies of them, and it's thus next to impossible to know of side effects. I think he sees several cases a year of patients with liver toxicity from supplements. I think in Feb. 2007 UCLA did 2 liver transplants on patients whose livers shut down from tylenol use. I do take a probiotic, but it's not as potent as VSL#3. I'm willing to take VSL#3, but it would be nice to see more scientific information about it that I can show my hepatologist.Marie

To: From: arman_shirin@...Date: Thu, 10 Apr 2008 12:17:31 -0700Subject: Re: Probiotic administration in patients with ileal pouch-anal anastomosis for UC

I have not heard of liver toxicity and VSL#3. Is that an issue? Is there a document about that?

arman_shirin (AT) yahoo (DOT) com

Probiotic administration in patients with ileal pouch-anal anastomosis for UC

The probiotic VSL#3 prevents pouchitis if started within a week of ileostomy closure and maintains remission following antibacterial treatment in patients with refractory or recurrent pouchitis.

Conclusions: We conclude that VSL#3 administration in patients with IPAA modulates the PDAI and expands the number of mucosal regulatory T cells………..

http://www3. interscience. wiley.com/ cgi-bin/abstract /117905168/ ABSTRACT? CRETRY=1 & SRETRY=0

Barb in Texas - Together in the Fight, Whatever it Takes!Son Ken (33) UC 91 - PSC 99 - Tx 6/21 & 6/30/07 @ Baylor in Dallas

Going green? See the top 12 foods to eat organic. __________________________________________________

[Guest guest]

Marie,

Go to: http://www.ncbi.nlm.nih.gov/ and enter

either “Probiotics” or “Probiotics & Pouchitis”. You’ll

find tons of studies there, you’ll just have to sort threw them.

Or you can go to http://www.google.com and enter “VLS #3

& Pouchitis” one of the sites you’ll see

is

http://www.vsl3.com/VSL3/uses-ileal-pouch.asp

it has plenty of info (including stuff for your doctor.)

Here are several studies

(only the tip of the iceberg):

http://www.cababstractsplus.org/google/abstract.asp?AcNo=20053141718

http://www.ncbi.nlm.nih.gov/pubmed/16973917

http://www.buyprobiotics.net/education/ProBioticsForHealth/Probiotic_p15_VSL_3.shtml

A good one (with

pictures!) http://enzymeuniversity.com/artman/publish/article_143.shtml

Good hunting….

Barb in Texas - Together in the Fight, Whatever it Takes!

Son Ken (33) UC 91 - PSC 99 - Tx 6/21 & 6/30/07 @ Baylor in

Dallas

,_._,___

[Guest guest]

Marie,

Go to: http://www.ncbi.nlm.nih.gov/ and enter

either “Probiotics” or “Probiotics & Pouchitis”. You’ll

find tons of studies there, you’ll just have to sort threw them.

Or you can go to http://www.google.com and enter “VLS #3

& Pouchitis” one of the sites you’ll see

is

http://www.vsl3.com/VSL3/uses-ileal-pouch.asp

it has plenty of info (including stuff for your doctor.)

Here are several studies

(only the tip of the iceberg):

http://www.cababstractsplus.org/google/abstract.asp?AcNo=20053141718

http://www.ncbi.nlm.nih.gov/pubmed/16973917

http://www.buyprobiotics.net/education/ProBioticsForHealth/Probiotic_p15_VSL_3.shtml

A good one (with

pictures!) http://enzymeuniversity.com/artman/publish/article_143.shtml

Good hunting….

Barb in Texas - Together in the Fight, Whatever it Takes!

Son Ken (33) UC 91 - PSC 99 - Tx 6/21 & 6/30/07 @ Baylor in

Dallas

,_._,___

[Guest guest]

Marie,

Go to: http://www.ncbi.nlm.nih.gov/ and enter

either “Probiotics” or “Probiotics & Pouchitis”. You’ll

find tons of studies there, you’ll just have to sort threw them.

Or you can go to http://www.google.com and enter “VLS #3

& Pouchitis” one of the sites you’ll see

is

http://www.vsl3.com/VSL3/uses-ileal-pouch.asp

it has plenty of info (including stuff for your doctor.)

Here are several studies

(only the tip of the iceberg):

http://www.cababstractsplus.org/google/abstract.asp?AcNo=20053141718

http://www.ncbi.nlm.nih.gov/pubmed/16973917

http://www.buyprobiotics.net/education/ProBioticsForHealth/Probiotic_p15_VSL_3.shtml

A good one (with

pictures!) http://enzymeuniversity.com/artman/publish/article_143.shtml

Good hunting….

Barb in Texas - Together in the Fight, Whatever it Takes!

Son Ken (33) UC 91 - PSC 99 - Tx 6/21 & 6/30/07 @ Baylor in

Dallas

,_._,___

[Guest guest]

>My hepatologist doesn't want me on VSL#3 because he's worried about

liver toxicity.

I'm post transplant, and my docs aren't worried by my VSL#3 even though

theoretically if there was a risk from it, the immune suppression might

make that risk worse. Right now I'm trying to get over a flare that

started when I tried lowering my dose of VSL#3, so all of my problems

have come from not taking it, not from taking it!

athan

[Guest guest]

>My hepatologist doesn't want me on VSL#3 because he's worried about

liver toxicity.

I'm post transplant, and my docs aren't worried by my VSL#3 even though

theoretically if there was a risk from it, the immune suppression might

make that risk worse. Right now I'm trying to get over a flare that

started when I tried lowering my dose of VSL#3, so all of my problems

have come from not taking it, not from taking it!

athan

[Guest guest]

>My hepatologist doesn't want me on VSL#3 because he's worried about

liver toxicity.

I'm post transplant, and my docs aren't worried by my VSL#3 even though

theoretically if there was a risk from it, the immune suppression might

make that risk worse. Right now I'm trying to get over a flare that

started when I tried lowering my dose of VSL#3, so all of my problems

have come from not taking it, not from taking it!

athan