Re: Armour contains calcium??!!! - letter to Forest

[Guest guest]

Hi,

I just wrote and email to Forest Pharm. about the use of calcium

sterate in Armour tablets themselves, and asking about other element

interactions. I would like to get hard data on interaction times

(delays) for element/mineral supplements. I assume it is too low to

cause an interaction, as Armour obviously does wrk (although my

question is - could it work *better* if there were no Ca in it at all..)

I plan to call them if I don't get a response.

The email to Forest is below,

Jim

---- (email to Forest)

I have read (but not found what I consdier to be definitive info)

that calcium (as well as iron) interferes with thyroid hormone

absorption in the gastrointestinal tract, leading to a " generally

accepted " practice of waiting 1 hour after taking Armour to take

calcium and 4 to take iron - although one person said they could not

find a Ca supplement that did not interfere even when seperated by

*12* hours) What is the " lower limit " of Ca and Fe intake that will

interfere, and are there any other elements that will? I assume

there is a lower limit for Ca, as calcium stearate is an inactive

ingredient for Armour itself, and the drug obviously works..

Particularly, in addition to Ca and Fe, will selenium, magnesium,

potassium, and titanium interfere? I know Se is found in the de-

iodinase enzmes and I presume may be required for the removal of

iodine in the T4->T3/RT3 conversion, and is also a useful supplement

as it has been shown to reduce TPO and TgAb concentrations (PMID

11932302 and 14757967), and magnesium is often deficient (so I have

read) in persons with hypothyroidism, and so is often supplemented.

Potassium is found in just about everything these days it seems, and

titanium is used ubiquitously in the white dye titanium dioxide in

many pharmaceuticals, including Armour. In my opinion , TiO2 is

totally uncessesary, and should be removed as while titanium is not

known to cause any problems with the human body, and generally stays

bound in TiO2 form due to it's high reactivity, it is not known *not*

to cause any negative interactions either. It is in everything, so

there is no suitable control population in which to look for adverse

effects)

I personally use a selenium supplement (Nature's Bounty - high Se

yeast 200mcg) which contains dicalcuium phosphate as the first

ingrident (I delay before taking that in case it's Ca concentration

is too high).

I am not however certain about Ca in my antidepressant and

antianxiety drugs - generic buporpion (75 mg), supplied by Teva, NDC

0093-0280-01; and lorazepam 1 mg, supplied by Pedinol Pharm. I

cannot find a reference to generic Lorazepam made by Pedinol, but the

previous supplier of my pharmacy (Mylan) has NDC 0378-2321-[01/05/10

depending on bottle size]. It's inactives are: lactose monohydrate,

microcrystalline cellulose, polacrilin potassium and sodium stearyl

fumarate [1].

The burpropion contains as inactives: colloidal silicon dioxide,

FD & C Blue No. 2 Aluminum Lake, FD & C Yellow No. 6 Aluminum Lake,

glutamic acid hydrochloride, hydroxypropyl cellulose, hypromellose,

magnesium stearate, maleic acid, microcrystalline cellulose,

polyethylene glycol 400, polyethylene glycol 6000, talc, and titanium

dioxide. I am not certain either of these contain Ca. (assumming

Pedinol uses the same inactives, which I assume it does)

Thank you,

Jim Witte

[1] Lorazepam: http://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?id=4145

[2] Burproion: http://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?id=2773

----

[Guest guest]

Hi,

I just wrote and email to Forest Pharm. about the use of calcium

sterate in Armour tablets themselves, and asking about other element

interactions. I would like to get hard data on interaction times

(delays) for element/mineral supplements. I assume it is too low to

cause an interaction, as Armour obviously does wrk (although my

question is - could it work *better* if there were no Ca in it at all..)

I plan to call them if I don't get a response.

The email to Forest is below,

Jim

---- (email to Forest)

I have read (but not found what I consdier to be definitive info)

that calcium (as well as iron) interferes with thyroid hormone

absorption in the gastrointestinal tract, leading to a " generally

accepted " practice of waiting 1 hour after taking Armour to take

calcium and 4 to take iron - although one person said they could not

find a Ca supplement that did not interfere even when seperated by

*12* hours) What is the " lower limit " of Ca and Fe intake that will

interfere, and are there any other elements that will? I assume

there is a lower limit for Ca, as calcium stearate is an inactive

ingredient for Armour itself, and the drug obviously works..

Particularly, in addition to Ca and Fe, will selenium, magnesium,

potassium, and titanium interfere? I know Se is found in the de-

iodinase enzmes and I presume may be required for the removal of

iodine in the T4->T3/RT3 conversion, and is also a useful supplement

as it has been shown to reduce TPO and TgAb concentrations (PMID

11932302 and 14757967), and magnesium is often deficient (so I have

read) in persons with hypothyroidism, and so is often supplemented.

Potassium is found in just about everything these days it seems, and

titanium is used ubiquitously in the white dye titanium dioxide in

many pharmaceuticals, including Armour. In my opinion , TiO2 is

totally uncessesary, and should be removed as while titanium is not

known to cause any problems with the human body, and generally stays

bound in TiO2 form due to it's high reactivity, it is not known *not*

to cause any negative interactions either. It is in everything, so

there is no suitable control population in which to look for adverse

effects)

I personally use a selenium supplement (Nature's Bounty - high Se

yeast 200mcg) which contains dicalcuium phosphate as the first

ingrident (I delay before taking that in case it's Ca concentration

is too high).

I am not however certain about Ca in my antidepressant and

antianxiety drugs - generic buporpion (75 mg), supplied by Teva, NDC

0093-0280-01; and lorazepam 1 mg, supplied by Pedinol Pharm. I

cannot find a reference to generic Lorazepam made by Pedinol, but the

previous supplier of my pharmacy (Mylan) has NDC 0378-2321-[01/05/10

depending on bottle size]. It's inactives are: lactose monohydrate,

microcrystalline cellulose, polacrilin potassium and sodium stearyl

fumarate [1].

The burpropion contains as inactives: colloidal silicon dioxide,

FD & C Blue No. 2 Aluminum Lake, FD & C Yellow No. 6 Aluminum Lake,

glutamic acid hydrochloride, hydroxypropyl cellulose, hypromellose,

magnesium stearate, maleic acid, microcrystalline cellulose,

polyethylene glycol 400, polyethylene glycol 6000, talc, and titanium

dioxide. I am not certain either of these contain Ca. (assumming

Pedinol uses the same inactives, which I assume it does)

Thank you,

Jim Witte

[1] Lorazepam: http://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?id=4145

[2] Burproion: http://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?id=2773

----