Utility of serum tumor markers, imaging, and biliary cytology for detecting cholangiocarcinoma in PSC

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There is limited information on test performance for

detecting cholangiocarcinoma in primary sclerosing cholangitis (PSC), particularly when used sequentially. This study aimed to characterize diagnostic performance of

serum carbohydrate antigen 19-9 (CA 19-9), ultrasonography,

computed tomography, magnetic resonance imaging, cholangiography,

and biliary cytologic techniques for detecting

cholangiocarcinoma in PSC. All consecutive patients

with PSC were screened and followed for development of cholangiocarcinoma from

2000 through 2006. Of 230 patients….. http://www.ncbi.nlm.nih.gov/pubmed/18785620

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