SAM-e and homocysteine

[Guest guest]

Fred;

Here's a good article on SAM-e and homocysteine, showing how SAM-e is

converted to homocysteine, and how homocysteine can then be converted

back to methionine and SAM-e again if there is adequate supply of folic

acid, vitamin B12 and betaine:

Mato JM, Lu SC 2005 Homocysteine, the bad thiol. Hepatology 41: 976-

979.

http://www3.interscience.wiley.com/cgi-bin/fulltext/110471811/PDFSTART

If you are taking vitamin supplements (including B12 and folate) and

are eating your spinach (Popeye was way ahead of his time!) then I

don't see a problem with SAM-e causing excess homocysteine accumulation.

Dave R.